Life as We Know It or Life as We Knew It may refer to:

• Life, as we know it on Earth, as described using standard biochemistry
• Life as We Know It (film), a 2010 romantic comedy film directed by Greg Berlanti
• Life as We Know It (TV series), a 2004 American television drama
• Life as We Know It (REO Speedwagon album), 1987
• Life as We Know It (Lonestar album), 2013, or the title track
• Life as We Know It (EP), by American Alternative rock band Wild Colonials
• "Life as We Knew It" (song), 1989 single by Kathy Mattea
• Life as We Knew It (novel), science fiction novel by Susan Beth Pfeffer

This disambiguation page lists articles associated with the title Life as We Know It.
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