Paquette was promoted to full professor at OSU in 1969 and was named Distinguished University Professor in 1987. He was elected a member of the National Academy of Sciences in 1984, and was the founding editor of the Electronic Encyclopedia of Reagents for Organic Synthesis (e-EROS).[3]
Paquette is best known for achieving the first total synthesis of the Platonic solid dodecahedrane.[4] He authored over 1300 peer-reviewed papers, 38 book chapters, and 17 books. He also lectured at various institutions both domestically and internationally.
Honors
Paquette's honors include Sloan Fellow, Guggenheim Fellow, ACS Award for Creative Work in Synthetic Organic Chemistry, and the Arthur C. Cope Scholar Award of the ACS.[5] In 1984 he was awarded the ACS Award for Creative Work in Synthetic Organic Chemistry and was elected to the National Academy of Sciences that same year.[6]
Scientific misconduct
In 1991, the Ohio State University investigatory panel found that Paquette had plagiarized a NSF proposal, that he was also a reviewer for, and included sections in a paper he published in the Journal of the American Chemical Society. The NSF's Office of Inspector General (OIG) found that Paquette knowingly "submitted falsified evidence for the purpose of disproving the misconduct in science charge" and made "false statements under oath in the OIG investigation concerning the authenticity of the evidence". The falsified evidence consisted of a computer disk that included a "'mock draft,' a copy of the paper's final draft that Paquette had marked up to look like an earlier draft" and was back-dated prior to Paquette's review of the NSF proposal and, importantly, prior to the manufacture of the disk. The US Secret Service also found that someone had attempted to erase the lot number of the disk. In 1998, the NSF entered into a binding settlement with Paquette: Paquette would voluntarily exclude himself from any federal funding for two years and the NSF would not "issue a finding of misconduct in science".[7][8][9]