Starting at the Sales Interchange in Pasay nearing its boundary with Taguig, the avenue heads east and crosses the South Luzon Expressway and PNR South Main Line railroad tracks. It enters Taguig, where it meets the intersection with Chino Roces Avenue Extension (formerly Pasong Tamo Extension) near the entrance to the Fort Andres Bonifacio at Gate 3. It continues across army property, winding past the Philippine Naval Hospital and Kagitingan Executive Golf Course and intersecting with Bayani Road. At Upper McKinley Road, Lawton traverses the McKinley Hillmixed-use development and the Philippine Army Headquarters, bending sharply north as it skirts the western side of Manila American Cemetery. The avenue ends at a fork in the road with 5th Avenue to the west, which leads to Bonifacio Global City, and Old Lawton Road to the east, which leads to the American Cemetery entrance.
As part of the Duterte administration's Build! Build! Build! Infrastructure Program, the avenue was expanded from four lanes (two lanes per direction) to six lanes (three lanes per direction). The project spans 3.1 kilometers (1.9 mi) and is divided into two phases. The road widening project is complemented by the construction of the Santa Monica-Lawton Bridge and the expected influx of vehicles once the bridge is opened. When completed, the travel time between Bonifacio Global City and Ninoy Aquino International Airport will be reduced by about 40%, and the road will accommodate more vehicles. Construction began on August 21, 2017,[3] and the first phase, spanning 1.34 kilometers (0.83 mi), was opened on November 17, 2020. The road widening project is expected to be fully completed in September 2021.[4]