Acasio was born in Los Angeles. She moved to Hawaii, and studied at the University of Hawaiʻi, earning a degree in geology.[2] She worked as a teacher and a substitute at over fifteen schools, including at Haaheo Elementary in Wainaku, and worked with multiple non-profits as an environmentalist.[3][4] She has two children.[4]
She was appointed on January 19, 2021 by Governor David Ige to the Hawaii Senate, representing District 1, Hilo, Hawaii. She served on the committees for Agriculture & Environment, Hawaiian Affairs, Human Services and Judiciary.[4]
Acasio wrote a letter in 2021 to the Department of Hawaiian Home Lands to request protesters, who some consider illegal squatters on public lands, to be allowed to remain camped on Mauna Kea.[6]
She faults wealthy investors for driving up cost of homes in Hawaii. She is quoted as saying in the Hawaii Tribune-Herald: “This allows wealthy investors to have a feeding frenzy on luxury homes. That frenzy ultimately drives up the cost of land and rental prices in Hawaii."[7]