Asante entered the 2007 season as the starting strong safety after transitioning from linebacker in the spring. He played in twelve games, starting ten of them.[2]
Asante started twelve games of the thirteen he played in 2008. He finished the 2008 season as |Nebraska's second-leading tackler with 67 tackles, including 45 solo tackles. He made at least five tackles in eight games, led by a career-high 13 stops at Oklahoma.
Asante finished his last year at Nebraska with a career-high 79 tackles, including 42 solo stops. He forced two fumbles and recorded two interceptions, one of which he returned for a touchdown. He started all 14 games in 2009 for a unit that led the nation in scoring defense and pass efficiency defense. He was selected to the first-team All-Big 12 team by conference coaches and Rival.com.[2]
Asante and the Browns agreed to a four-year contract worth about $1.96 million on July 16, 2010.
Asante was waived by the Browns on September 4, 2010.
On September 5, 2010 Asante was signed to the Browns practice squad.
Tampa Bay Buccaneers
Asante was signed off the Tampa Bay Buccaneers practice squad after a season-ending injury to starting rookie Cody Grimm. He appeared in the final two games of the 2010 season, recording an interception against Drew Brees in the season finale against the New Orleans Saints. He was released on August 30, 2012.
Indianapolis Colts
Asante signed a reserve/future contract with the Indianapolis Colts on December 31, 2012.[4]