Langston High School may refer to:

• Langston High School (Tennessee) in Johnson City, Tennessee established in 1893 and named for John Mercer Langston
• Langston High School (Arkansas) in Hot Springs, Arkansas where Ike Thomas, Mamie Phipps Clark and Edith Mae Irby Jones went
• John M. Langston High School in Danville, Virginia named for John Mercer Langston and where C. B. Claiborne went

• Langston Hughes High School in Fairburn, Georgia

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