Safe Harbor Water Power Corporation provides picnic areas, boat ramps, playgrounds and other public recreation facilities at several locations on both sides of the lake.
Lake Clarke is home to Long Level Marina, Safe Harbor's boat-access areas, Susquehanna Yacht Club, Lake Clarke Rescue Inc., and two private marinas that are located on the York County side of the lake. The United States Coast Guard Auxiliary Flotilla 19-5 (Division 19 (5th District Northern Region (NR)) patrols the area of Lake Clarke and is based out of Auxiliary Station Long Level, 1960 Long Level Road, Wrightsville, on the York County side of the lake.