PROFILPELAJAR.COM

Lactivicin

Lactivicin
Names
IUPAC name
2-(4-Acetamido-3-oxo-1,2-oxazolidin-2-yl)-5-oxooxolane-2-carboxylic acid
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
  • InChI=1S/C10H12N2O7/c1-5(13)11-6-4-18-12(8(6)15)10(9(16)17)3-2-7(14)19-10/h6H,2-4H2,1H3,(H,11,13)(H,16,17)
    Key: ZUEKKUYIXILDAF-UHFFFAOYSA-N
  • CC(=O)NC1CON(C1=O)C2(CCC(=O)O2)C(=O)O
Properties
C10H12N2O7
Molar mass 272.213 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Lactivicin is a non-beta-lactam antibiotic that is active against a range of Gram-positive and Gram-negative bacteria.[1] Lactivicin demonstrates a similar affinity for penicillin-binding proteins to beta-lactam antibiotics and is also susceptible to beta-lactamase enzymes.[2]

References

  1. ^ Nozaki Y, Katayama N, Harada S, Ono H, Okazaki H (1989). "Lactivicin, a naturally occurring non-beta-lactam antibiotic having beta-lactam-like action: biological activities and mode of action". J. Antibiot. 42 (10): 84–93. doi:10.7164/antibiotics.42.84. PMID 2493440.
  2. ^ Harada S, Tsubotani S, Hida T, Ono H, Okazaki H (1986). "Structure of lactivicin, an antibiotic having a new nucleus and similar biological activities to β-lactam antibiotics". Tetrahedron Letters. 27 (51): 6229–6232. doi:10.1016/S0040-4039(00)85439-8.

Content Disclaimer

Informasi ini disarikan dari Wikipedia dan disajikan kembali untuk tujuan edukasi. Konten tersedia di bawah lisensi CC BY-SA 3.0. Kami tidak bertanggung jawab atas ketidakakuratan data yang bersumber dari kontribusi publik tersebut.

  1. The information displayed on this website is sourced in part or in whole from Wikipedia and has been adapted for the purpose of restating it. We strive to provide accurate and relevant information, however:
  2. There is no guarantee of absolute accuracy. Wikipedia is an open, collaborative project that can be edited by anyone, so information is subject to change.
  3. It is not intended to constitute professional advice. The content displayed is for informational and educational purposes only. For important decisions (e.g., medical, legal, or financial), please consult a professional.
  4. Content copyright. Wikipedia is licensed under the Creative Commons Attribution-ShareAlike License (CC BY-SA). This means that content may be reused with appropriate attribution and shared under a similar license.
  5. Responsible use. Any risk arising from the use of information from this website is entirely the responsibility of the user.