Four women decide to leave their homes unexpectedly without telling anyone their whereabouts, to rebel against their marriages and their lives as housewives that did not turn out as they thought. However, in addition to the trip, a murder will bring their lives together.
In August 2021, the series was announced as La rebelión de las esposas, being one of the titles to be produced by Pantaya and Elefantec Global.[4] On 7 January 2022, filming of the series began in Mexico City, with the title being changed to simply La rebelión.[1] On 14 January 2022, Aracely Arámbula, Daniela Vega, Ana Serradilla and Adriana Paz were cast in the lead roles.[2] On 29 October 2022, it was announced that the series would premiere on Vix+, following TelevisaUnivision's acquisition of Pantaya a month prior.[5][6] On 10 November 2022, Vix released an official trailer for the series.[3]