Peters HC, et al. (2001). "Conserved Kv4 N-terminal domain critical for effects of Kv channel-interacting protein 2.2 on channel expression and gating"....

toxin selectively inhibits Kv4.2 voltage-gated potassium channels by acting as a gating modifier. TLTx is part of the family of Kv4-specific tarantula toxins...

from the venom of the giant crab spider Heteropoda venatoria, which block Kv4.2 voltage-gated potassium channels. Heteropodatoxins are purified from the...

inhibiting the activation of voltage-gated potassium channels, most specifically Kv4.2 and Kv2.1, by raising its activation threshold. Hanatoxin is a spider toxin...

acts on potassium channels, blocking Kv1.3 and slowing the deactivation of Kv4.2. BmP02 is not toxic to humans or mice. The BmP02 toxin is a component of...

needed] The Ito1 is generated by voltage-gated K+ channels Kv1.4, Kv4.2, and (especially) Kv4.3; these channels undergo ball-and-chain inactivation to terminate...

structure of hpTX2, a toxin from Heteropoda venatoria spider that blocks Kv4.2 potassium channel. Protein Science 9(11), 2059-67. "Spiders in Bermuda"...

hyperpolarizing A-type current mediated by potassium channel KV4.2. miR-324-5p downregulates KV4.2, exacerbating conditions that lead to seizure onset, and...

lymphocytic leukemia. Dipeptidyl peptidase-like protein 6 (DPPX) is a subunit of Kv4.2 potassium channels expressed in the hippocampus, cerebellum, striatum, and...

humans (hKv1.1) and squid (sqKv1.A). It also affects members of Kv4 family (Kv4.1 and Kv4.2) and Drosophila ether-à-go-go channels. The mode of action of...

Shaker-related: Kv1.4 (KCNA4) Kvα4.x - Shal-related: Kv4.1 (KCND1), Kv4.2 (KCND2), Kv4.3 (KCND3) Kvα10.x: Kv10.2 (KCNH5) Passes current more easily in the inward...

Quinidine also blocks certain voltage-gated potassium channels (e.g., Kv1.4, Kv4.2, hERG, among others), acts as an antimuscarinic and alpha-1 blocker, and...

serrulatus. Ts8 is a selective inhibitor of the voltage-gated potassium channel Kv4.2 The neurotoxin Ts8 can be derived from the venom from the Brazilian yellow...

regulation of CREB, and increasing cellular excitability via inhibiting Kv4.2. ΔFosB (DeltaFosB) – a gene transcription factor – overexpression in the...

Shrier A (December 2000). "Localization and enhanced current density of the Kv4.2 potassium channel by interaction with the actin-binding protein filamin"...

Potassium voltage-gated channel subfamily D member 3 also known as Kv4.3 is a protein that in humans is encoded by the KCND3 gene. It contributes to the...

voltage-gated channel, Shal-related subfamily, member 1 (KCND1), also known as Kv4.1, is a human gene. Voltage-gated potassium (Kv) channels represent the most...

Electrocardiography Interpretation". Anesthesia Progress. 53 (2): 53–64. doi:10.2344/0003-3006(2006)53[53:foei]2.0.co;2. PMC 1614214. PMID 16863387. Lote, C. (2012)....

on other tested potassium channels (Kv1.2, Kv1.3, Kv1.4, Kv1.5, Kv1.6, Shaker IR, Kv2.1, Kv3.1, Kv4.2 and Kv4.3). APEKTx1 selectively blocks Kv1.1 channels...

membrane potential. Effect on potassium channels JZTX-V mainly affects the Kv4.2 potassium channel current by shifting its activation curve to a more depolarized...

CITEREFDiochot1999 (help). Phrixotoxin-1 and -2 are similar to heteropodatoxin, which also has a blocking activity on Kv4.2 channels (Chagot 2004) harv error: no...

blocker of the voltage-gated potassium channel Kv1.3, and a gating modifier of Kv4.3 channels. The Ctri9577 toxin is a component of the venom of the scorpion...

reported to not regulate Kv4.2 or Kv4.3, but has been found to accelerate, and left-shift the voltage dependence of, inactivation of Kv4.3-KChIP2 channel complexes...

(2001). "Different effects of the Ca(2+)-binding protein, KChIP1, on two Kv4 subfamily members, Kv4.1 and Kv4.2". FEBS Lett. 499 (3): 205–209. Bibcode:2001FEBSL...

the A-type potassium current. AmmTX3 is a specific pore blocker of Kv4.2 and Kv4.3 channels of mice. This high-affinity blockade depends on the expression...

acts on potassium channels, blocking Kv1.3 and slowing the deactivation of Kv4.2. BmP02 is not toxic to humans or mice. The scorpion occasionally appears...

Shal-related: Kv4.1 (KCND1), Kv4.2 (KCND2), Kv4.3 (KCND3) Kvα10.x: Kv10.2 (KCNH5) Kvα11.x - ether-a-go-go potassium channels: Kv11.1 (KCNH2) - hERG, Kv11.2 (KCNH6)...

novel EF-hand protein interacting with presenilin 2 and voltage-gated potassium channel subunit Kv4". J. Biol. Chem. 277 (17): 14965–75. doi:10.1074/jbc...

54 nM). BmTx3 blocks primarily the Kv4.x proteins and has a higher affinity for Kv4.1 channels than for Kv4.2 and Kv4.3 channels. The second functional...

the KCNQ1 Kv α subunit, but it also regulates hERG, Kv2.1, Kv3.x, Kv4.x and Kv12.2 in heterologous co-expression experiments and/or in vivo. Co-assembly...

epilepsy. In this model, there is downregulation of the A-type encoding Kv4.2 channel. This channel is involved in limiting backpropagation of action...

other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal...

function mutation in KCND2, encoding pore-forming alpha subunit of the cardiac Kv4.2 potassium channel. Gout caused by aberrant D-lactate dehydrogenase Birk–Landau-Perez...

subtypes of both delayed rectifier (KV2.1 and KV2.2) and A-type rapidly inactivating (KV4.1, KV4.2 and KV4.3) voltage-gated potassium channels. At a concentration...

containing EF-hand-like domains. They are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, and hence neuronal excitability...

mediates complex formation between peptidase homologues and Kv4 channels". Mol. Cell. Neurosci. 29 (2): 320–32. doi:10.1016/j.mcn.2005.02.003. PMID 15911355...

KCNE1 and Kv4.2, but KCNE1 was found to slow the gating and increase macroscopic current of Kv4.3 in HEK cells. In contrast, channels formed by Kv4.3 and...

complexes with Kv4.2 and KCNE4. Deletion of Kcne4 in mice impaired ventricular myocyte Ito, a current generated at least in part by Kv4.2. Although mouse...

forms complexes with Kv1.5 and with Kv4.2 in adult mouse ventricular myocytes. KCNE2 increases currents though Kv4.2 channels and slows their inactivation...

Kv3 and Kv4. The Kv1 channel primarily influences the repolarization of the axon. The Kv2 channel is characteristically activated slower. The Kv4 channels...

until Cys29 and Arg33 until Cys36. Discrepin blocks voltage-gated Shal-type (Kv4.x) K+ channels in cerebellar granular cells. These A-type K+ channels regulate...

Kv2.2, Kv2.1/9.3 and the A-type potassium channel Kv4.2, with affinity (IC50) of 12.7 nM, 21.4 nM, 7.2 nM and 1.2 nM, respectively. No activity on Kv4.1...

S2CID 40595323. Jerng HH, Qian Y, Pfaffinger PJ (2005). "Modulation of Kv4.2 channel expression and gating by dipeptidyl peptidase 10 (DPP10)". Biophys...

toxins for subtypes of voltage-dependent potassium channels in the Kv2 and Kv4 subfamilies". Molecular Pharmacology. 62 (1): 48–57. doi:10.1124/mol.62.1...

other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal...

1999 Socorro LINEAR  · 3.9 km MPC · JPL 25330 1999 KV4 — May 17, 1999 Catalina CSS APO +1km 3.2 km MPC · JPL 25331 Berrevoets 1999 KY4 Berrevoets May...

the tombs, providing information and plans of the open tombs. KV1 KV2 KV3 KV4 KV5 KV6 KV7 KV8 KV9 KV10 KV11 KV12 KV13 KV14 KV15 KV16 KV17 KV18 KV19 KV20...

storeroom and conservation laboratory; KV55 as a photographic darkroom; and KV4, the tomb of Ramesses XI, as a place to take meals. Four Egyptian foremen –...

East Valley of the Kings Discovered 1825 Excavated by Kent R. Weeks (1995) Decoration Opening of the Mouth Layout Labyrinth ← Previous KV4 Next → KV6...

upper wing, just like in more expensive series. No longer in production. KV4 Since 1999 (Korean Series) / 2001 (USA Series), features Seymour Duncan JB...

inhibited by GxTX-1 are the Kv2.2 and Kv4.3 channels. Kv2.2 is located predominantly in δ-cells of primate islets. Kv4.3 is mainly of importance in the...

to designate tombs located in the West Valley (of the Kings). KV1 KV2 KV3 KV4 KV5 KV6 KV7 KV8 KV9 KV10 KV11 KV12 KV13 KV14 KV15 KV16 KV17 KV18 KV19 KV20...

yet to be granted by Fife Council. https://www.youtube.com/watch?v=rP9RqcIvKv4 61994 Working "The Welsh Mountaineer" to Blaenau Ffestiniog in August 2012...

Senrikyu 5344 Ryabov (5690) 1992 EU 6500 Kodaira (7753) 1988 XB (25330) 1999 KV4 (65679) 1989 UQ (523972) 1999 CW8 Asteroid spectral types Yang, Bin; Jewitt...

frequently merged with the Type 2 pattern in contemporary practice. Type 1 has a coved type ST elevation with at least 2 mm (0.2 mV) J-point elevation and a...

Guardian. Retrieved 24 October 2014. The National Archives, Kew, file no. KV4/227 p. 9. Keating, H.R.F. (1982). Whodunit? – a guide to crime, suspense...

Specification Reference: 55 PS (40 kW) at 6200 rpm, 7.1 kg⋅m (70 N⋅m) at 3800 rpm (KV4 series Sambar Touring) 58 PS (43 kW) at 6000 rpm, 7.5 kg⋅m (74 N⋅m) at 4400 rpm...

circumstances. While he had a tomb prepared for himself in the Valley of the Kings (KV4), it was left unfinished and only partly decorated since Ramesses XI instead...

other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal...

journal. The Head was found in 1924 by Pierre Lacau and Rex Engelbach in KV4 (the tomb of Ramses XI), which was used as a storehouse for the excavation...

significance for the history of the Eastern Mediterranean". Quaternary Research. 74 (2): 207. Bibcode:2010QuRes..74..207K. doi:10.1016/j.yqres.2010.07.010. Roberts...

tomb, and then twice during the construction of the adjacent tombs KV3 and KV4. During the first looting, only perishable products such as oil were removed;...

(KV7.1, KV7.2, KV7.4, and KV7.5) but it has also been found to inhibit KV1.3 (and the Drosophila homolog shaker), KV2.1 (KCNB1) and KV4 (and its Drosophila...

Ramesses X (c. 1111–1107 BC), where she appears with Ra-Horakhty; the tomb (KV4) of Pharaoh Ramesses XI (c. 1107–1077 BC), where she appears with many deities...

PN9 (24443) 2000 OG (24445) 2000 PM8 24761 Ahau 25143 Itokawa (25330) 1999 KV4 (26379) 1999 HZ1 (26663) 2000 XK47 (27002) 1998 DV9 (29075) 1950 DA (30825)...

outward potassium current downregulation in human heart failure: a decrease in Kv4.3 mRNA correlates with a reduction in current density". Circulation. 98 (14):...

(24443) 2000 OG (24445) 2000 PM8 † 24761 Ahau 25143 Itokawa (25330) 1999 KV4 (26379) 1999 HZ1 (26663) 2000 XK47 (27002) 1998 DV9 † (29075) 1950 DA (30825)...

highly conserved human potassium channel gene (NGK2-KV4; KCNC1) to chromosome 11p15". Genomics. 15 (2): 405–11. doi:10.1006/geno.1993.1075. PMID 8449507...

sodium and potassium channels reversibly, including mammalian rNav1.2, rNav1.4, mNav1.6, Kv4.3 hERG-potassium channels and arachnid VdNav. In DRG cells, the...

"Functional specification of CCK+ interneurons by alternative isoforms of Kv4.3 auxiliary subunits". eLife. 9 e58515. doi:10.7554/eLife.58515. ISSN 2050-084X...

Potapova IA, Cohen IS, Doronin SV (September 2007). "Voltage-gated ion channel Kv4.3 is associated with Rap guanine nucleotide exchange factors and regulates...

MPC · JPL 150469 2000 KV4 — May 27, 2000 Socorro LINEAR PHO 2.5 km MPC · JPL 150470 2000 KT28 — May 28, 2000 Socorro LINEAR  · 2.7 km MPC · JPL 150471...

belonging to Thutmose I, were recovered from the shaft in the burial chamber of KV4, together with remains of royal funerary equipment belonging to several other...

October 2014. Retrieved 24 October 2014. The National Archives, Kew, file no. KV4/227 p. 9. "Document". Document. London. 14 July 2015. BBC. BBC Radio 4. Retrieved...

JPL 274222 2008 JS40 — May 15, 2008 Kitt Peak Spacewatch  · 1.2 km MPC · JPL 274223 2008 KV4 — May 27, 2008 Kitt Peak Spacewatch  · 1.5 km MPC · JPL 274224...

outward potassium current downregulation in human heart failure: a decrease in Kv4.3 mRNA correlates with a reduction in current density". Circulation. 98 (14):...

(2005). "Spironolactone and its main metabolite canrenoic acid block hKv1.5, Kv4.3 and Kv7.1+minK channels". British Journal of Pharmacology. 146 (1): 146–161...

LINEAR NYS 1.2 km MPC · JPL 108337 2001 KX3 — May 17, 2001 Socorro LINEAR V 1.8 km MPC · JPL 108338 2001 KV4 — May 17, 2001 Socorro LINEAR EUN 2.3 km MPC ·...

list (376344) 2011 HL27 27 April 2010 list (376363) 2011 KV4 3 June 2010 list (376519) 2012 LZ24 2 April 2010 list (376520) 2012 LC25 17 February 2010 list...

martensii, potently inhibits rKv1.1, rKv1.2 and hKv1.3 channels but does not affect rKv1.4, rKv1.5, hKv3.1, rKv4.3, and hERG channels even at high concentrations...

MPC · JPL 376363 2011 KV4 — June 3, 2010 WISE WISE  · 4.4 km MPC · JPL 376364 2011 KG9 — February 14, 2010 Kitt Peak Spacewatch 3:2 · SHU 5.7 km MPC · JPL...

5'-cyclic nucleotide phosphodiesterases ARF1 (ADP Ribosylation factor 1) A type (Kv4.3; Shal-related subfamily, member 3) voltage-gated potassium channels Nitric...

function. Four of these subfamilies, Kv1 (Shaker), Kv2 (Shab), Kv3 (Shaw) and Kv4 (Shal), consist of pore-forming alpha subunits that associate with different...

church Kulubnarti Kumma (Nubia) Kurna Kurt Sethe Kushite religion KV1 KV2 KV3 KV4 KV5 KV6 KV7 KV8 KV9 KV10 KV11 KV12 KV13 KV14 KV15 KV16 KV18 KV19 KV20 KV21...

a non-conventional traffic route to the cell surface used by KChIP1 and Kv4 potassium channels". Biochem. J. 418 (3): 529–40. doi:10.1042/BJ20081736...

HU82 — April 24, 2009 Mount Lemmon Mount Lemmon Survey Tj (2.99) 5.9 km MPC · JPL 266679 2009 KV4 — May 22, 2009 Hibiscus Teamo, N. RAF 1.3 km MPC · JPL 266680...

epithelial K+ channels KCNE1/KCNQ1 Voltage-gated K+ channels Kv1.3, Kv1.5, and Kv4.3 Glutamate Receptors The following carriers and pumps are influenced by...

Peak Spacewatch  · 2.0 km MPC · JPL 674037 2015 KU4 — March 6, 2011 Mount Lemmon Mount Lemmon Survey  · 1.3 km MPC · JPL 674038 2015 KV4 — August 13, 2012...

Kitt Peak Spacewatch  · 2.0 km MPC · JPL 401756 2013 KW3 — March 16, 2007 Kitt Peak Spacewatch  · 3.2 km MPC · JPL 401757 2013 KV4 — October 15, 2004 Mount...

Palomar NEAT  · 2.1 km MPC · JPL 223633 Rosnyaîné 2004 KJ1 Rosnyaîné May 17, 2004 Saint-Sulpice B. Christophe  · 2.4 km MPC · JPL 223634 2004 KV4 — May 18,...

Haleakala Pan-STARRS 1 H 460 m MPC · JPL 653142 2014 KV4 — November 16, 2001 Kitt Peak Spacewatch  · 2.4 km MPC · JPL 653143 2014 KK7 — April 5, 2014 Haleakala...

7, 2006 Mount Lemmon Mount Lemmon Survey  · 1.0 km MPC · JPL 417416 2006 KV4 — May 19, 2006 Mount Lemmon Mount Lemmon Survey V 650 m MPC · JPL 417417...

JPL 629714 2003 KV4 — May 22, 2003 Kitt Peak Spacewatch  · 710 m MPC · JPL 629715 2003 KZ7 — May 23, 2003 Kitt Peak Spacewatch  · 2.5 km MPC · JPL 629716...