Search Results: Kv1.2 potassium channel

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KCNA2
Senin, 2025-11-17 23:03:52

Potassium voltage-gated channel subfamily A member 2 also known as Kv1.2 is a protein that in humans is encoded by the KCNA2 gene. Potassium channels...

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Hg1 (toxin)
Rabu, 2026-03-18 11:41:17

it selectively inhibits the potassium channel Kv1.3 and, with a lower affinity, channels Kv1.1 and Kv1.2. The Hg1 toxin is named after the Mexican scorpion...

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Pandinus imperator toxin
Kamis, 2025-09-18 03:18:17

B, Kv1.2, and SK potassium channels. Pi4 binds to Shaker B potassium channels, the Drosophila homologue of the voltage-gated potassium channel Kv1.1....

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Hefutoxin
Jumat, 2026-04-10 22:21:45

the potassium channels Kv1.2 and Kv1.3 and slows the activation of Kv1.3. The kappa- Hefutoxin 1 and 2 (κ- hefutoxin1/2) are toxic components in the venom...

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Ts15
Senin, 2021-10-25 03:01:35

It targets voltage-gated potassium channels, primarily the subtypes Kv1.2 and Kv1.3. Ts15 can be isolated from the venom of Tityus serrulatus, otherwise...

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Pi5
Rabu, 2025-06-11 06:27:33

the African emperor scorpion Pandinus imperator. Pi5 inhibits human Kv1.2 and Kv1.3 channels as well as Drosophila Shaker B potassium channels. Pi5 is...

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Kv1.1
Jumat, 2026-04-24 00:53:31

Potassium voltage-gated channel subfamily A member 1 also known as Kv1.1 is a shaker related voltage-gated potassium channel that in humans is encoded...

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Kalicludine
Sabtu, 2025-12-27 20:13:58

Kalicludine (AsKC) is a blocker of the voltage-dependent potassium channel Kv1.2 found in the snakeslocks anemone Anemonia viridis (Anemonia sulcata), which...

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Spinoxin
Minggu, 2026-02-01 09:07:38

effects by inhibiting voltage-gated potassium channels, specifically Kv1.2 and Kv1.3. Spinoxin is isolated from the venom of the Malaysian black scorpion...

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Cm28
Kamis, 2025-10-16 01:38:59

Centruroides margaritatus, selectively blocks voltage-gated potassium channels KV1.2 and KV1.3 with high affinity. It also suppresses the activation of human CD4+...

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KCNA3
Kamis, 2025-09-25 05:35:28

voltage-gated channel, shaker-related subfamily, member 3, also known as KCNA3 or Kv1.3, is a protein that in humans is encoded by the KCNA3 gene. Potassium channels...

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OSK3
Sabtu, 2025-10-11 01:35:39

subfamily and targets the voltage-gated potassium channels KCNA2 (Kv1.2), and KCNA3 (Kv1.3). OSK3 is secreted from the venom gland of Orthochirus scrobiculosus...

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Butantoxin
Kamis, 2025-09-18 20:47:06

Butantoxin reversibly blocks the voltage-gated K+ channels Shaker B and Kv1.2, and the Ca2+-activated K+ channels KCa 1.1 and KCa 3.1. Butantoxin is one...

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Hemitoxin
Kamis, 2023-11-02 21:24:25

Iranian scorpion Hemiscorpius lepturus, which reversibly blocks Kv1.1, Kv1.2 and Kv1.3 voltage-gated K+ channels. HTX is a neurotoxin derived from the...

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Cvill7
Sabtu, 2025-12-20 15:47:02

Particularly, Cvill7 exerts a high affinity for Kv1.2, with weaker effects on Kv1.1 and Kv1.3. | colspan="2" |Cvill7 |- |Superfamily |Scorpion toxins |-...

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MeuKTX
Minggu, 2021-10-24 04:13:53

eupeus. This short-chain peptide blocks potassium channels, such as Kv1.1, Kv1.2 and Kv1.3. MeuKTX is a neurotoxin found in the venom of the scorpion Mesobuthus...

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BscTx3
Senin, 2024-12-23 07:08:30

potassium channels Kv1.1, Kv1.2, Kv1.3, Kv1.6 as well as Drosophila Shaker IR channels. The IC50 values for these channels are 172.59 nM for Kv1.2/KCNA2, 2245...

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Calyx of Held
Minggu, 2026-07-26 08:20:57

channels present: Kv1.1, Kv1.2, Kv1.3, and Kv7.5. Kv1.1 and Kv1.2 are located in the transition zone between the axon and the terminal, while Kv1.3 Kv7.5 are...

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CboK7
Kamis, 2025-10-16 01:38:43

α-KTx 2.24, is a toxin produced by a species of scorpion, Centruroides bonito. It blocks voltage-gated K+ channels, with the highest affinity for Kv1.2 channels...

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Tst26
Selasa, 2025-05-27 12:45:03

stigmurus, a species of Brazilian scorpion. Tst26 selectively blocks Kv1.2 and Kv1.3 channels. Tst26 is named after the species it was discovered from...

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KCNA2-related disorders
Kamis, 2026-04-09 18:11:06

KCNA2-related disorders are caused by mutations to the Kv1.2 channels encoded by the KCNA2 gene. These neurological disorders are associated with a spectrum...

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Hongotoxin
Kamis, 2025-07-17 00:33:35

Shaker-type (Kv1) K+ channels. HgTX1 shows high affinity with Kv1.1, Kv1.2, Kv1.3 voltage-gated potassium channels, but much lower affinity with Kv1.6 (see...

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Kaliseptine
Kamis, 2026-02-19 16:56:43

potassium channel KV1.2. The IC50 for inhibition of the KV1.2 K+ channel by kaliseptine is 140 nM as compared to 2.1 nM by DTXI itself. The KV1.2 channel is...

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Potassium channel
Sabtu, 2026-06-20 09:34:29

conductance Ca(2+)-activated K+ channel". Biophysical Journal. 63 (2): 583–590. Bibcode:1992BpJ....63..583C. doi:10.1016/S0006-3495(92)81630-2. PMC 1262182...

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Maurotoxin
Sabtu, 2026-04-18 16:32:34

channels (IK) Several types of voltage-gated potassium channels (Kv1.1, Kv1.2, Kv1.3 and shaker B) The structural and pharmacological features of MTX...

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LmKTx10
Selasa, 2026-01-27 05:33:17

channels of the family Kv1. It has a higher selectivity for the Kv1.3 potassium channel (KCNA3), compared to other channels in the Kv1 family. The Name LmKTx10...

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BgK
Senin, 2025-11-17 22:15:10

BgK blocks the Kv1.1, Kv1.2, and Kv1.3 channels with similar affinities. IC50 is 6 nM for Kv1.1, 15 nM for Kv1.2, and 10 nM for Kv1.3. Meanwhile, tests...

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Margatoxin
Sabtu, 2025-06-14 04:28:55

Margatoxin (MgTX) is a peptide that selectively inhibits Kv1.3 voltage-dependent potassium channels. It is found in the venom of Centruroides margaritatus...

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Sulfatide
Kamis, 2026-02-19 23:27:35

number of clusters of sodium channels at the nodes of Ranvier. Additionally, Kv1.2 channels are moved from the paranodal position to the juxtaparanodal position...

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Parabutoxin
Sabtu, 2025-06-21 06:28:29

cysteine residues. Usually, binding sites of Kvα1-blocking toxins (Kv1.1, Kv1.2, Kv1.3) include a lysine and a hydrophobic residue, but PBTx1, PBTx2 and...

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Developmental bioelectricity
Minggu, 2026-06-07 07:34:26

Gaofeng; Edmundson, Mathew; Telezhkin, Vsevolod; et al. (2016). "The Role of Kv1.2 Channel in Electrotaxis Cell Migration". Journal of Cellular Physiology...

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Voltage-gated potassium channel
Sabtu, 2026-06-20 02:14:05

Kv1.1 (KCNA1), Kv1.2 (KCNA2), Kv1.3 (KCNA3), Kv1.5 (KCNA5), Kv1.6 (KCNA6), Kv1.7 (KCNA7), Kv1.8 (KCNA10) Kvα2.x - Shab-related: Kv2.1 (KCNB1), Kv2.2 (KCNB2)...

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APEKTx1
Sabtu, 2025-08-30 20:13:03

potassium channel Kv1.1 with no effect on other tested potassium channels (Kv1.2, Kv1.3, Kv1.4, Kv1.5, Kv1.6, Shaker IR, Kv2.1, Kv3.1, Kv4.2 and Kv4.3). APEKTx1...

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Mesobuthus eupeus
Selasa, 2026-05-19 01:05:49

6) from M. martensii, potently inhibits rKv1.1, rKv1.2 and hKv1.3 channels but does not affect rKv1.4, rKv1.5, hKv3.1, rKv4.3, and hERG channels even...

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Tityustoxin
Jumat, 2026-05-22 20:14:34

with the alpha-dendrotoxin binding site on the cloned Kv1.2 K+ channel". Molecular Pharmacology. 44 (2): 430–436. doi:10.1016/S0026-895X(25)13197-0. ISSN 0026-895X...

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SHTX
Kamis, 2025-12-18 17:56:43

It also works on potassium (Kv1.2) channels as a blocker, the precise mechanism is still unknown. SHTX IV is a type 2 sea anemone sodium channel toxin...

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List of MeSH codes (D12.776.543)
Jumat, 2025-08-15 03:47:17

311 – kv1.1 potassium channel MeSH D12.776.543.550.425.750.900.124.342 – kv1.2 potassium channel MeSH D12.776.543.550.425.750.900.124.358 – kv1.3 potassium...

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MCD peptide
Jumat, 2024-08-16 16:43:38

voltage-gated potassium channels (Kv channels), including Kv1.1, Kv1.6, and less potently to Kv1.2. Accordingly, MCD peptide can act in various regions of...

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ImKTx88
Sabtu, 2026-03-28 21:50:53

ImKTx88 is a selective inhibitor of the Kv1 ion channel family that can be isolated from the venom of the Isometrus maculatus (lesser brown scorpion)...

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Cobatoxin
Sabtu, 2025-09-13 05:11:25

β, and γ. These 3 families differ in structure. Cobatoxin 1 and 2 both block the Kv1.1 K+-channels in mice and the Shaker B K+ channels in insects, which...

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Kendriya Vidyalaya No. 2, Vizag
Sabtu, 2026-02-21 08:59:53

and one Navy Children School in the Naval Campus. The other three being KV1, NSB; KV Malkapuram; NCS, NSB, Vizag. The school has a fairly big campus...

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KCNA5
Rabu, 2025-07-23 22:29:50

voltage-gated channel, shaker-related subfamily, member 5, also known as KCNA5 or Kv1.5, is a protein that in humans is encoded by the KCNA5 gene. Potassium channels...

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Psora-4
Senin, 2026-06-08 16:39:08

Psora-4 is an experimental drug that acts as a selective inhibitor of the Kv1.3 potassium channel. It has immunomodulatory effects, suppressing the proliferation...

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LmKTT-1a
Minggu, 2025-09-28 07:24:22

toxin, it both inhibits trypsin activity and blocks Kv1 channels with a weak selectivity towards Kv1.3 channels. The LmKTT-1a toxin was first identified...

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Cation channel superfamily
Kamis, 2025-10-02 00:53:46

Kv1.1 (KCNA1), Kv1.2 (KCNA2), Kv1.3 (KCNA3), Kv1.5 (KCNA5), Kv1.6 (KCNA6), Kv1.7 (KCNA7), Kv1.8 (KCNA10) Kvα2.x - Shab-related: Kv2.1 (KCNB1), Kv2.2 (KCNB2)...

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Stichodactyla toxin
Jumat, 2026-07-17 16:35:26

metalloprotease 23) and MFAP-2 (microfibril-associated glycoprotein 2). The ShK peptide blocks potassium (K+) ion channels Kv1.1, Kv1.3, Kv1.6, Kv3.2 and KCa3.1 with...

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KCNA4
Selasa, 2025-07-15 11:20:40

Potassium voltage-gated channel subfamily A member 4 also known as Kv1.4 is a protein that in humans is encoded by the KCNA4 gene. It contributes to the...

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Clofazimine
Jumat, 2026-05-22 09:26:47

diabetes. Because the Kv1.3-high effector memory T cells (TEM) are actively involved in the development of these diseases, and Kv1.3 activity is essential...

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Anuroctoxin
Senin, 2024-12-23 07:08:38

potent blocker of Kv1.3 (Kd= 0.73 nM) potassium channels. Besides Kv1.3/KCNA3 channels, Anuroctoxin also significantly inhibits Kv1.2 (Kd = 6 nM) potassium...

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Antonello Bonci
Sabtu, 2026-03-28 21:54:47

interaction between sigma-1 receptor and Kv1.2 shapes neuronal and behavioral responses to cocaine". Cell. 152 (1–2): 236–47. doi:10.1016/j.cell.2012.12.004...

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KV2
Minggu, 2026-07-26 10:27:32

tomb of Ramesses IV, and is located low in the main valley, between KV7 and KV1. It has been open since antiquity and contains a large amount of graffiti...

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Cadherin-2
Jumat, 2026-07-31 00:56:46

that the arrhythmias were likely due to ion channel remodeling and aberrant Kv1.5 channel function. These animals showed a prolonged action potential duration...

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Heteroscodratoxin-1
Rabu, 2025-05-28 20:36:53

and KV3.4) or delayed rectifier potassium channels (KV1.1, KV1.2, KV1.3, KV1.5, KV1.6, KV1.2/ KV1.5, or KVLQT1), or on sodium and calcium channels has...

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Pandinus imperator (Pi3) toxin
Selasa, 2025-06-24 09:53:41

scorpion venom. It is a potent blocker of voltage-gated potassium channel, Kv1.3 and is closely related to another peptide found in the venom, Pi2. Pi3...

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KCNAB2
Kamis, 2025-07-17 00:42:22

Pryke J, Dolly JO (Aug 1999). "Subunit composition of Kv1 channels in human CNS". J. Neurochem. 73 (2): 849–58. doi:10.1046/j.1471-4159.1999.0730849.x. PMID 10428084...

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Cortactin
Jumat, 2025-10-31 13:40:40

E, Cachero TG, Morielli AD (October 2002). "Tyrosine phosphorylation of Kv1.2 modulates its interaction with the actin-binding protein cortactin". J....

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Ramesses VII
Sabtu, 2026-06-20 14:28:27

was buried in Tomb KV1 upon his death. Finely carved wall reliefs in Ramesses VII's KV1 tomb The Tomb Corridor of Ramesses VII's KV1 tomb His mummy has...

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Pandinotoxin
Sabtu, 2025-06-14 04:28:26

channels of the subfamily A member 2 (Kv1.2/KCNA2) [1] and they can reversibly block the shaker B potassium-channels (Kv1.1 sub-family). The residue K27,...

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PTPRA
Kamis, 2025-11-20 06:58:13

participates in the m1 muscarinic acetylcholine receptor-dependent regulation of Kv1.2 channel activity". EMBO J. 18 (1): 109–18. doi:10.1093/emboj/18.1.109. PMC 1171107...

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Alpha-actinin-2
Senin, 2026-04-27 12:04:56

"alpha-actinin-2 couples to cardiac Kv1.5 channels, regulating current density and channel localization in HEK cells". FEBS Letters. 473 (2): 188–94. doi:10...

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Gintonin
Jumat, 2025-11-07 11:35:19

(2013). "Activation of lysophosphatidic acid receptor by gintonin inhibits Kv1.2 channel activity: Involvement of tyrosine kinase and receptor protein tyrosine...

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ImKTX58
Minggu, 2025-11-16 18:17:52

demonstrates a high selectivity for the Kv1.3 channel over other voltage-gated potassium channels, such as Kv1.1, Kv1.2, Kv1.5, as well as calcium-activated potassium...

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OdK2
Sabtu, 2026-05-16 01:51:56

α-KTx family, and selectively blocks the voltage-gated potassium channel Kv1.3 (KCNA3). OdK2 is an acronym for the species of origin, the substrate of...

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KCNA6
Sabtu, 2025-07-19 03:39:09

Potassium voltage-gated channel subfamily A member 6 also known as Kv1.6 is a protein that in humans is encoded by the KCNA6 gene. The protein encoded...

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GJC3
Sabtu, 2023-03-04 06:49:56

In both PNS and CNS myelinated axons, Cx29 is precisely colocalized with Kv1.2 voltage-gated K+ channels, where both proteins are concentrated in the juxtaparanode...

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Kappa-KTx2.5
Senin, 2026-05-11 15:24:44

asparagine-24 (N24) residue of κ-KTx2.5 interacts with aspartic acid-348 (D348) of Kv1.2 at a distance of 3.7 Å, affecting only one subunit. Lysine-23 (K23) in the...

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List of MeSH codes (D12.776.157)
Jumat, 2025-08-15 03:43:00

124 – kv1.1 potassium channel MeSH D12.776.157.530.400.600.900.500.186 – kv1.2 potassium channel MeSH D12.776.157.530.400.600.900.500.217 – kv1.3 potassium...

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Shaker (gene)
Rabu, 2025-03-26 18:32:21

structure determination of AgTx2-MTX chimera, a new potential blocker for Kv1.2 channel, derived from MTX and AgTx2 scorpion toxins". Protein Science. 17...

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Episodic ataxia
Selasa, 2025-07-15 11:08:14

encodes the voltage-gated potassium channel KV1.1, are responsible for this subtype of episodic ataxia. KV1.1 is expressed heavily in basket cells and...

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Jackson King V
Sabtu, 2025-06-14 00:45:53

but with dot inlays, no binding, and rosewood fretboard. KV1(Artist Signature Series) The KV1 is a Dave Mustaine signature model and is the first commercially-sold...

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BF9
Sabtu, 2025-05-24 01:45:19

inhibit both serine proteases and potassium channels (more specifically the Kv1.3 channel). Venom basic protease inhibitor IX, also named BF9, is derived...

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KCNA10
Sabtu, 2023-03-04 03:33:37

Potassium voltage-gated channel subfamily A member 10 also known as Kv1.8 is a protein that in humans is encoded by the KCNA10 gene. The protein encoded...

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Dendrotoxin
Minggu, 2025-09-07 23:45:02

For example, Wang et al. showed that the interaction of dendrotoxin-K with KV1.1 is mediated by its lysine residues in both the N-terminus and the β-turn...

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XEN-D0101
Selasa, 2026-06-30 10:15:40

XEN-D0101 is a selective antagonist of the voltage-gated potassium channel Kv1.5. Atrial fibrillation is the main focus of Xention’s drug development, as...

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Human uses of scorpions
Kamis, 2025-11-06 00:47:13

peptides. An important physiological role of the KCNA3 channel, also known as KV1.3, is to help maintain large electrical gradients for the sustained transport...

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Ctri9577
Senin, 2026-06-22 19:18:15

scorpion, which is a potent blocker of the voltage-gated potassium channel Kv1.3, and a gating modifier of Kv4.3 channels. The Ctri9577 toxin is a component...

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BrMT
Sabtu, 2024-11-23 11:36:04

degree also isoforms found in humans (hKv1.1) and squid (sqKv1.A). It also affects members of Kv4 family (Kv4.1 and Kv4.2) and Drosophila ether-à-go-go channels...

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GRIA2
Senin, 2025-10-27 23:17:06

related to that found in K+ channels, such as the human Kv1.1 channel. The pre-mRNA of the human Kv1.1 channel is also subject to A-to-I RNA editing. Glutamate...

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Twentieth Dynasty of Egypt
Selasa, 2026-08-04 21:13:55

discovery by Howard Carter in 1922. Ramesses VII's only monument is his tomb, KV1.[citation needed] Almost nothing is known about Ramesses VIII's reign, which...

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Amitriptyline
Senin, 2026-08-03 02:13:39

Friederich P (May 2007). "Amitriptyline is a potent blocker of human Kv1.1 and Kv7.2/7.3 channels". Anesthesia and Analgesia. 104 (5): 1256–64, tables of...

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KCNE4
Senin, 2025-09-29 15:45:50

strongly inhibits Kv1.1 and Kv1.3 channels when co-expressed in HEK cells and in Xenopus laevis oocytes, while leaving Kv1.2 and Kv1.4 currents unaffected...

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Kendriya Vidyalaya No. 1, AFS, Lohegaon, Pune
Sabtu, 2026-06-27 13:40:31

Force Station, Pune, OR KV1. Among the facilities are: Class rooms 43 Physics Lab 1 Biology Lab 1 Chemistry Lab 1 Computer Labs 4 (2 Primary, 1 Secondary)...

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BmK NSPK
Kamis, 2024-06-06 07:45:16

with BmKTX (Buthus martensii kaliotoxin), which is a previously discovered Kv1.3 channel blocker, BmK NSPK showed 79% sequence homology. Furthermore, BmKTX...

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Team Secret
Rabu, 2026-07-29 09:52:44

lineup. October 8 Danilo "kv1" Michelini joined. On January 8, 2024, Team Secret announced the formation of a new Counter-Strike 2 roster including Danish...

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Valley of the Kings
Jumat, 2026-08-07 04:26:30

signs for the tombs, providing information and plans of the open tombs. KV1 KV2 KV3 KV4 KV5 KV6 KV7 KV8 KV9 KV10 KV11 KV12 KV13 KV14 KV15 KV16 KV17 KV18...

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Discovery of the tomb of Tutankhamun
Minggu, 2026-07-12 23:31:20

Weeks 2016, pp. 6–7. Tyldesley 2012, pp. 24–27. Thompson 2015, pp. 2–4. Reid 2015, pp. 2–5. James 2000, p. 224. Riggs 2019, pp. 15–16. Tyldesley 2012, p...

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Panchkula
Kamis, 2026-07-23 04:21:34

Vidyalaya No. 1 (KV1), Chandimandir Cantonment Kendriya Vidyalaya No. 2 (KV2), Chandimandir Cantonment Litera Heritage School, Sector-14, Ext.-2, Panchkula...

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BmKTX
Senin, 2025-11-03 11:14:00

is a scorpion neurotoxin which blocks the voltage gated potassium channel Kv1.3. The name BmK part of the toxin is derived from the name of the scorpion...

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List of burials in the Valley of the Kings
Kamis, 2026-07-30 19:13:46

also used to designate tombs located in the West Valley (of the Kings). KV1 KV2 KV3 KV4 KV5 KV6 KV7 KV8 KV9 KV10 KV11 KV12 KV13 KV14 KV15 KV16 KV17 KV18...

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Sisu Nasu
Kamis, 2024-11-14 01:48:53

12 in tail unit. NA-111GT A signal station version. NA-120 GT NA-120 GT KV1 Armoured variant used in UN-operations. NA-122 A version that carries a 120 mm...

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BmP02
Sabtu, 2026-06-13 05:24:21

scorpion. The toxin acts on potassium channels, blocking Kv1.3 and slowing the deactivation of Kv4.2. BmP02 is not toxic to humans or mice. The BmP02 toxin...

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Dave Mustaine
Senin, 2026-07-27 17:29:15

meaning it had two of the longer fins from the RR). The reshaped Mustaine KV1 model had slightly shorter fins, Kahler bridge and Seymour Duncan TB-5 bridge...

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Quinidine
Selasa, 2026-06-02 14:49:48

Quinidine also blocks certain voltage-gated potassium channels (e.g., Kv1.4, Kv4.2, hERG, among others), acts as an antimuscarinic and alpha-1 blocker,...

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HsTx1
Minggu, 2025-08-31 14:13:54

scorpion Heterometrus spinifer. HsTx1 is a very potent inhibitor of the rat Kv1.3 voltage-gated potassium channel. HsTx1 stands for Heterometrus spinifer...

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Endocannabinoid system
Sabtu, 2026-06-27 11:21:12

Immunohistochemistry experiments demonstrated that CB1 is co-localized with GIRK and Kv1.4 potassium channels, suggesting that these two may interact in physiological...

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Kaliotoxin
Rabu, 2026-07-29 09:26:22

Kaliotoxin (KTX) inhibits potassium flux through the Kv1.3 voltage-gated potassium channel and calcium-activated potassium channels by physically blocking...

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Repolarization
Senin, 2026-04-27 05:53:59

membrane to re-establish the resting potential. The four types are Kv1, Kv2, Kv3 and Kv4. The Kv1 channel primarily influences the repolarization of the axon...

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Gambierol
Minggu, 2025-08-31 14:48:03

especially Kv1.1-1.5 channels and the Kv3.1 channel. Kv1.1-1.5 channels are responsible for repolarization of the membrane potential. The Kv1.3 channel...

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Middle Khmer
Minggu, 2026-06-28 01:12:08

khmère". Bulletin de l'École Française d'Extrême-Orient (in French). 53 (2): 375–451. doi:10.3406/befeo.1967.5052. Jenner, Philip N. (1974). "The Development...

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Palmitoyl acyltransferase
Kamis, 2025-02-13 07:46:34

receptor subunit GluR1 and GluR2, GABAA receptor gamma2 subunit, aquaporin, KV1.1, rhodopsin, beta2-adrenergic receptor, and PSD-95. https://swisspalm.org/enzymes...

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Essential fatty acid
Senin, 2025-12-29 04:01:08

1994). "External blockade of the major cardiac delayed-rectifier K+ channel (Kv1.5) by polyunsaturated fatty acids". Proceedings of the National Academy of...

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KCNA7
Minggu, 2022-04-17 10:12:23

Potassium voltage-gated channel subfamily A member 7 also known as Kv1.7 is a protein that in humans is encoded by the KCNA7 gene. The protein encoded...

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Christine Beeton
Kamis, 2026-03-26 02:19:00

the first person able to show the significant benefits of blocking Kv1.1 and Kv1.3 channels with kaliotoxin - a component of scorpion venom - as a preventative...

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Morvan's syndrome
Selasa, 2026-07-14 04:28:34

neuromyotonia. It is believed that antibodies to the Shaker-type K+ channels (the Kv1 family) are the type of potassium channel most strongly associated with acquired...

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Kaamelott: The First Chapter
Rabu, 2026-08-05 06:13:16

"KAAMELOTT - PREMIER VOLET sortira au cinéma le 21 juillet.#KaamelottLeFilm #KV1" (Tweet) – via Twitter. "Kaamelott : Premier Volet sortira en salle le 21...

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Anti-VGKC-complex encephalitis
Minggu, 2026-05-17 22:07:08

the radioimmunoprecipitation assay, only 3 (3%) had antibodies towards the Kv1 subunit of the VGKC channel, 55 (57%) had antibodies against Leucine-rich...

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KCND2
Sabtu, 2025-07-19 13:14:47

Doerksen KW, Steele DF, Fedida D (2002). "N-terminal PDZ-binding domain in Kv1 potassium channels". FEBS Lett. 531 (3): 529–537. doi:10.1016/S0014-5793(02)03572-X...

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Sigma-1 receptor
Sabtu, 2026-07-04 05:11:11

has been shown to appear in a complex with voltage gated K+ channels (Kv1.4 and Kv1.5), leading to the idea that σ1 receptors are auxiliary subunits. σ1...

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Olivierus martensii
Selasa, 2026-04-21 05:51:36

treatments. BmP02 acts on potassium channels, blocking Kv1.3 and slowing the deactivation of Kv4.2. BmP02 is not toxic to humans or mice. The scorpion occasionally...

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Cardiac transient outward potassium current
Sabtu, 2025-11-01 08:44:58

[citation needed] The Ito1 is generated by voltage-gated K+ channels Kv1.4, Kv4.2, and (especially) Kv4.3; these channels undergo ball-and-chain inactivation...

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4-Aminopyridine
Kamis, 2026-07-23 07:57:08

biophysics.[citation needed] It is a relatively selective blocker of members of Kv1 (Shaker, KCNA) family of voltage-activated K+ channels. However, 4-AP has...

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Neuroprotection
Kamis, 2026-07-23 23:19:09

fluid of sporadic amyotrophic lateral sclerosis patients alters Nav1.6 and Kv1.6 channel expression in rat spinal motor neurons". Brain Research. 1255:...

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List of unnumbered minor planets: 1996
Senin, 2026-07-27 20:52:21

Small Bodies Node. 2019. Retrieved 31 January 2022. Johnston, Wm. Robert (2 January 2022). "List of Known Trans-Neptunian Objects". Johnston's Archive...

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Heteropodatoxin
Rabu, 2023-07-19 23:33:55

channel Kv4.2. Recombinant heteropodatoxin-2 blocks the potassium channels Kv4.1, Kv4.2 and Kv4.3, but not Kv1.4, Kv2.1, or Kv3.4. Heterpodatoxin-2 most likely...

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Dmitry Lelyushenko
Kamis, 2026-04-30 07:47:24

brigades – a new type of formation – which were to be armed with T-34 and KV1 tanks. In this capacity he had command over numerous future Soviet ‘leading...

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Pharmacodynamics of spironolactone
Selasa, 2025-12-23 06:16:24

Eva (2005). "Spironolactone and its main metabolite canrenoic acid block hKv1.5, Kv4.3 and Kv7.1+minK channels". British Journal of Pharmacology. 146 (1):...

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Psoralen
Jumat, 2026-07-24 08:15:56

Heike Wulff (November 2005). "Design of PAP-1, a selective small molecule Kv1.3 blocker, for the suppression of effector memory T cells in autoimmune diseases"...

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Ts8
Sabtu, 2026-01-31 05:25:58

Ts8-FragII has a small inhibitory effect on the Kv1.3 channel. The inhibition caused by the neurotoxin Ts8 on Kv4.2 channels increases with repeated activation...

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AsKC11
Jumat, 2026-05-15 12:34:42

potassium channels, Kv1.1-1.4 channels, and showed a small inhibition of Kv1.6. channels. AsKC11 binding is reversible. For GIRK1/2 channel activation...

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List of unnumbered trans-Neptunian objects
Jumat, 2026-07-03 08:23:58

30.1 AU". Minor Planet Center. Archived from the original on 2 November 2025. Retrieved 2 November 2025. 5561 trans-Neptunian objects How many dwarf planets...

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KCNQ1
Jumat, 2026-07-24 04:12:00

channel, since experimental data suggests that there are 4 alpha subunits and 2 beta subunits in this complex. KVLQT1/KCNE1 channels are taken up from the...

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List of minor planets: 697001–698000
Rabu, 2026-04-01 21:19:33

697817 2017 KV1 — December 10, 2004 Kitt Peak Spacewatch  · 2.7 km MPC · JPL 697818 2017 KR6 — June 30, 2008 Kitt Peak Spacewatch  · 2.2 km MPC · JPL...

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Scaffold protein
Selasa, 2026-03-24 06:08:23

Large Tumor Suppressor Binds to p56 lck Tyrosine Kinase and Shaker Type Kv1.3 Potassium Channel in T Lymphocytes". Journal of Biological Chemistry. 272...

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GRIA3
Senin, 2025-10-27 23:16:02

structure is related to that found in K+ channels (e.g., human Kv1.1 channel). The human Kv1.1 channel pre mRNA is also subject to A to I RNA editing. The...

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AmmTX3
Selasa, 2026-06-02 14:48:10

channels almost completely. A-type potassium currents can be generated by Kv1.4, Kv3.3, Kv3.4, all members of Kv4 and Erg3 channels. The influence of AmmTX3...

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HgeTx1
Senin, 2024-12-23 07:50:44

1016/s0041-0101(98)00148-2. PMID 9792172. Mouhat, S.; et al. (2005). "Contribution of the functional dyad of animal toxins acting on voltage-gated Kv1-type channels"...

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DLG4
Kamis, 2025-07-31 20:47:58

Steele DF, Fedida D (November 2002). "N-terminal PDZ-binding domain in Kv1 potassium channels". FEBS Lett. 531 (3): 529–37. Bibcode:2002FEBSL.531..529E...

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List of minor planets: 426001–427000
Rabu, 2026-04-01 20:51:25

29, 2012 Mount Lemmon Mount Lemmon Survey NYS 1 km MPC · JPL 426197 2012 KV1 — March 29, 2012 Kitt Peak Spacewatch  · 1.5 km MPC · JPL 426198 2012 KK2...

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List of cis-regulatory RNA elements
Senin, 2024-10-07 04:32:38

element Vimentin 3′ UTR protein-binding region Voltage-gated potassium-channel Kv1.4 IRES Wingless localisation element 3 (WLE3) xerDC RNA motif YbhL leader...

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Index of ancient Egypt–related articles
Sabtu, 2026-08-01 05:55:26

Kulubnarti church Kulubnarti Kumma (Nubia) Kurna Kurt Sethe Kushite religion KV1 KV2 KV3 KV4 KV5 KV6 KV7 KV8 KV9 KV10 KV11 KV12 KV13 KV14 KV15 KV16 KV18 KV19...

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List of minor planets: 892001–893000
Rabu, 2026-07-01 02:48:00

Mount Lemmon Survey HOF 2.1 km MPC · JPL 892394 2015 JN26 — May 14, 2015 Haleakala Pan-STARRS 1  · 2.4 km MPC · JPL 892395 2015 KV1 — April 10, 2015 Haleakala...

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Lesional demyelinations of the central nervous system
Minggu, 2026-07-19 23:17:30

Wulff H, Calabresi PA, Allie R, et al. (June 2003). "The voltage-gated Kv1.3 K(+) channel in effector memory T cells as new target for MS". J. Clin...

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Genetically encoded voltage indicator
Senin, 2026-07-13 19:40:27

findings: (1) GEVIs contain a fluorescent protein FRET pair, e.g. VSFP1, (2) Single opsin GEVIs, e.g. Arch, (3) Opsin-FP FRET pair GEVIs, e.g. MacQ-mCitrine...

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GRIK2
Selasa, 2026-02-24 06:02:47

pore loop structure is similar to that found in K+ channels (e.g. the human Kv1.1 channel, whose pre-mRNA is also subject to A to I RNA editing). The diversity...

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Tyrosin-protein kinase Lck
Kamis, 2026-04-16 03:22:52

discs large tumor suppressor binds to p56lck tyrosine kinase and Shaker type Kv1.3 potassium channel in T lymphocytes". The Journal of Biological Chemistry...

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KCNAB3
Rabu, 2024-07-17 05:39:27

Isbrandt D, Pongs O (Feb 1999). "Coexpression of the KCNA3B gene product with Kv1.5 leads to a novel A-type potassium channel". J Biol Chem. 273 (52): 35095–101...

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Tamulotoxin
Selasa, 2026-06-02 14:50:00

(calcium-activated potassium channel), respectively. Another suggested target is the Kv1.6 channel, a voltage-gated potassium channel. There are two suggestions for...

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LGI1
Jumat, 2026-06-05 08:50:15

"Antibodies to Kv1 potassium channel-complex proteins leucine-rich, glioma inactivated 1 protein and contactin-associated protein-2 in limbic encephalitis...

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Michael G. Hanna
Senin, 2026-05-18 13:50:51

(1999). "A novel mutation in the human voltage-gated potassium channel gene (Kv1.1) associates with episodic ataxia type 1 and sometimes with partial epilepsy"...

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Potassium channel blocker
Selasa, 2026-06-23 13:40:46

voltage-gated Kv2.1 potassium channel currents. a very potent inhibitor of the rat Kv1.3 voltage-gated potassium channel Voigt N, Dobrev D (2016). "Atrial-Selective...

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Corticotropin-releasing hormone receptor
Minggu, 2025-09-28 13:39:48

neuronal excitability in the hippocampus by modulating potassium channels (KV1 subfamily), increasing population spike amplitudes through presynaptic mechanisms...

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List of minor planets: 99001–100000
Senin, 2026-06-15 07:04:15

NEAT  · 3.2 km MPC · JPL 99787 2002 JM146 — May 15, 2002 Haleakala NEAT V 1.2 km MPC · JPL 99788 2002 KV1 — May 16, 2002 Socorro LINEAR KOR 2.9 km MPC ·...

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1st Guards Cavalry Corps
Selasa, 2025-12-23 06:21:25

traditional sabre of the Cossack horsemen. The cavalrymen, along with the T34 and KV1 tanks wielded by the 112th Tank Division battled ferociously against the...

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Index of biophysics articles
Selasa, 2025-09-02 20:37:54

KCNT2 KCNV1 KCNV2 Kenneth Stewart Cole Kim Sung-Hou Kir2.1 Kir2.6 Kir6.2 Kv1.1 KvLQT1 KvLQT2 KvLQT3 L-type calcium channel Lamellar structure Lamellipodium...

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KCNE1
Selasa, 2025-10-21 19:26:29

co-expressed with the Kv1.1 α subunit in Chinese Hamster ovary (CHO) cells, KCNE1 traps the N-type (rapidly inactivating) Kv1.4 α subunit in the ER/Golgi...

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KCNE2
Selasa, 2025-09-16 05:02:47

that forms complexes with Kv1.5 and with Kv4.2 in adult mouse ventricular myocytes. KCNE2 increases currents though Kv4.2 channels and slows their inactivation...

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Unconventional myosin-Va
Sabtu, 2025-10-04 16:16:29

MYO5B are involved with Kv1.5 (encoded by Potassium voltage-gated channel subfamily A member 5, KCNA5) in the myocytes. Kv1.5 is associated with the...

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KCNAB1
Sabtu, 2025-07-19 13:14:43

discs large tumor suppressor binds to p56lck tyrosine kinase and Shaker type Kv1.3 potassium channel in T lymphocytes". J. Biol. Chem. 272 (43): 26899–904...

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SGK1
Selasa, 2026-02-24 06:07:42

Cardiac and epithelial K+ channels KCNE1/KCNQ1 Voltage-gated K+ channels Kv1.3, Kv1.5, and Kv4.3 Glutamate Receptors The following carriers and pumps are...

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DUSP3
Kamis, 2025-07-17 00:10:23

Swanson R (Feb 1995). "Confirmation of the assignment of the gene encoding Kv1.3, a voltage-gated potassium channel (KCNA3) to the proximal short arm of...

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List of minor planets: 643001–644000
Rabu, 2026-04-01 21:14:39

Spacewatch  · 2.2 km MPC · JPL 643633 2006 KV1 — May 19, 2006 Needville W. G. Dillon, M. M. Eastman  · 2.2 km MPC · JPL 643634 2006 KP10 — May 19, 2006...

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PTPRM
Kamis, 2025-11-20 07:23:37

brain cells. PTPmu has been shown to increase the mRNA of the K+ channel Kv1.5 in cardiac myocytes when CHO cells expressing PTPmu are cultured with cardiac...

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List of minor planets: 732001–733000
Rabu, 2026-04-01 21:22:54

km MPC · JPL 732733 2014 KV1 — May 20, 2005 Mount Lemmon Mount Lemmon Survey  · 2.2 km MPC · JPL 732734 2014 KE3 — April 2, 2010 WISE WISE  · 1.9 km...

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Guangxitoxin
Kamis, 2026-04-23 23:29:09

Gaisano HY, Salapatek AM, Backx PH, Wheeler MB (August 2001). "Members of the Kv1 and Kv2 voltage-dependent K(+) channel families regulate insulin secretion"...

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List of minor planets: 458001–459000
Minggu, 2026-05-10 07:01:47

JQ29 — January 30, 2008 Kitt Peak Spacewatch H 490 m MPC · JPL 458721 2011 KV1 — January 11, 2010 Kitt Peak Spacewatch  · 3.1 km MPC · JPL 458722 2011 KK12...

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SHC3
Kamis, 2025-12-18 14:33:59

adaptor proteins differentially modulate the phosphorylation and biophysics of Kv1.3 ion channel by SRC kinase". The Journal of Biological Chemistry. 277 (15):...

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Discrepin
Selasa, 2026-06-09 22:50:11

toxin BmTx3 to its receptor site, where other K+ channel blockers (Kv1-, Kv3.4-, Kv4.2/4.3 family blockers) were unable to compete with this toxin. These...

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MLC1
Sabtu, 2025-07-19 13:33:42

homology with the KCNA1 shaker-related voltage-gated potassium channel (Kv1.1). This analysis suggests that MLC1 may be a cation channel. GRCh38: Ensembl...

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List of minor planets: 508001–509000
Rabu, 2026-04-01 20:59:34

May 2, 2016 Haleakala Pan-STARRS 1  · 2.1 km MPC · JPL 508432 2016 KV1 — September 8, 2008 Siding Spring SSS  · 2.0 km MPC · JPL 508433 2016 KU2 — January...

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Ssm spooky toxin
Minggu, 2026-05-31 09:16:11

SsTx inhibits all KCNQ subtypes (KV7.1, KV7.2, KV7.4, and KV7.5) but it has also been found to inhibit KV1.3 (and the Drosophila homolog shaker), KV2.1...

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List of minor planets: 328001–329000
Rabu, 2026-03-25 22:52:59

JPL 328340 2008 KV1 — May 26, 2008 Kitt Peak Spacewatch WIT 1.2 km MPC · JPL 328341 2008 KP2 — May 27, 2008 Kitt Peak Spacewatch  · 2.1 km MPC · JPL 328342...

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Potassium channel tetramerisation domain
Minggu, 2023-12-03 23:24:38

the basis of sequence similarity and function. Four of these subfamilies, Kv1 (Shaker), Kv2 (Shab), Kv3 (Shaw) and Kv4 (Shal), consist of pore-forming...

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KCNE5
Senin, 2025-09-29 21:14:47

but not in oocytes. Although it has no known effects on hERG (Kv11.1) or Kv1.x family channel activity, KCNE5 inhibits Kv2.1 activity 50% and accelerates...

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Multiple sclerosis drug pipeline
Selasa, 2026-03-31 11:28:41

suppress myelin-reactive effector memory T cells by blocking voltage-gated Kv1.3 channels in these cells. hydralazine: Due to its ability to damage myelin...

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Gene therapy for epilepsy
Selasa, 2026-06-23 20:46:52

tone, it is possible to restore balance between inhibition and excitation. Kv1.1 is a voltage-gated potassium channel encoded by the KCNA1 gene. It is widely...

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GABRA3
Rabu, 2025-10-22 11:33:37

alter chloride permeability of the GABA receptor. At the time of discovery, Kv1.1 mRNA was the only previously known mammalian coding site containing both...

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Stichodactyla helianthus
Selasa, 2026-06-23 12:22:19

"Durable Pharmacological Responses from the Peptide ShK-186, a Specific Kv1.3 Channel Inhibitor That Suppresses T Cell Mediators of Autoimmune Disease"...

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DLG1
Sabtu, 2025-12-06 04:34:13

discs large tumor suppressor binds to p56lck tyrosine kinase and Shaker type Kv1.3 potassium channel in T lymphocytes". The Journal of Biological Chemistry...

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