cystine knot (also known as ICK or Knottin) is a protein structural motif containing three disulfide bridges. Knottins are one of three folds in the cystine...

delta and kappa families of conotoxins have a knottin or inhibitor cystine knot scaffold. The knottin scaffold is a very special disulfide-through-disulfide...

inhibitor cystine knot motif (ICK motif), thus defining the whole protein as a knottin. This three-dimensional arrangement confers the protein remarkable stability...

affects cell proliferation. The structure reveals an inhibitor cystine knot (knottin)-like fold, comprising three beta strands. Jouvensal, L.; Quillien, L.;...

suffusus suffusus β-toxin II SCOP classification Class Small proteins Fold Knottins (small inhibitors, toxins, lectins) Superfamily Scorpion toxin-like Family...

"Tying pest insects in knots: the deployment of spider-venom-derived knottins as bioinsecticides". Pest Manag. Sci. 75 (9): 2437–2445. doi:10.1002/ps...

and Alo-3. Alo-3 was the first known peptide from insects to exhibit the knottin fold. It has a higher level of activity against the fungal species Candida...

Angiogenesis with Contrast Microbubbles Conjugated to Integrin-Binding Knottin Peptides". Journal of Nuclear Medicine. 51 (3): 433–40. doi:10.2967/jnumed...

on this website. Spinoxin belongs to the class of small proteins with knottin folds resulting from the four disulfide bonds. The superfamily spinoxin...

Hanatoxin SCOP classification Class Small proteins Fold Knottins (small inhibitors, toxins, lectins) Superfamily omega toxin-like Family Spider toxins...

In 2011, Folding@home began simulations of the dynamics of the small knottin protein EETI, which can identify carcinomas in imaging scans by binding...

M, King GF (2013). "The insecticidal neurotoxin Aps III is an atypical knottin peptide that potently blocks insect voltage-gated sodium channels". Biochem...

the native-state structure due to the rarity of knots in known proteins. Knottins are small, diverse and stable proteins with important drug design potential...

domains contain a hair-pin loop like structure, similar to that found in knottins but with a different pattern of disulfide bonds. It has been shown that...

through disulfide knot', thus, structurally defines this protein as a knottin. It has two natural degradation products, namely CSTX-2a and CSTX-2b, which...

Jennifer R.; Pentelute, Bradley L. (October 31, 2017). "Heterochiral Knottin Protein: Folding and Solution Structure". Biochemistry. 56 (43): 5720–5725...

to the huwentoxin-1 family of inhibitory spider peptides based on its knottin backbone that consists of three crossing disulfide bridges...

putative antimicrobial CRPs include lipid transfer proteins, thionins, knottins, heveins, and snakins. Additionally, some CRPs have allergenic, ɑ-amylase...

a family of non-cyclic trypsin inhibitors from squash plants known as knottins or inhibitor cystine knots than they are to the other cyclotides. It is...