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Karate competitions at the 2021 SEA Games took place at Ninh Bình Province Sports Gymnasium in Ninh Bình, Vietnam^[1] from 18 to 20 May 2022.^[2]

  *   Host nation (Vietnam)

Rank	Nation	Gold	Silver	Bronze	Total
1	Vietnam*	7	2	6	15
2	Indonesia	4	8	2	14
3	Malaysia	4	0	6	10
4	Thailand	0	4	5	9
5	Laos	0	1	0	1
6	Philippines	0	0	8	8
7	Cambodia	0	0	3	3
Totals (7 entries)		15	15	30	60

Event	Gold	Silver	Bronze
Men's individual	Ahmad Zigi Zaresta Yuda  Indonesia	Phạm Minh Đức  Vietnam	Muhammad Aiqal Asmadie  Malaysia
			John Enrico Vasquez  Philippines
Women's individual	Nguyễn Thị Phương  Vietnam	Monsicha Tararattanakul  Thailand	Rebecca Cyril Torres  Philippines
			Krisda Putri Aprilia  Indonesia
Men's team	Indonesia Albiadi Andy Tomy Aditya Mardana Andi Dasril Dwi Dharmawan	Thailand Nathawut Kanabkaew Phanudet Khananpao Pikanet Sukyik	Malaysia Ivan Oh Thomson Hoe Emmanuel Leong
			Vietnam Lê Hồng Phúc Giang Việt Anh Phạm Minh Đức
Women's team	Vietnam Nguyễn Ngọc Trâm Lưu Thị Thu Uyên Nguyễn Thị Phương	Indonesia Anugerah Nurul Lucky Dian Monika Nababan Emilia Sri Hanandyta	Malaysia Khaw Yee Voon Chang Sin Yi Lim Hui Ling
			Philippines Nicole Erika Dantes Rebecca Cyril Torres Sarah Pangilinan

Event	Gold	Silver	Bronze
−60 kg	Ari Saputra  Indonesia	Võ Văn Hiền  Vietnam	Prem Kumar Selvam  Malaysia
			Jayson Ramil Macaalay Ordoñez  Philippines
−67 kg	Sureeya Sankar Hari Sankar  Malaysia	Tebing Hutapea  Indonesia	Chalermpon Piwlaaiad  Thailand
			Đặng Hồng Sơn  Vietnam
−75 kg	Sharmendran Raghonathan  Malaysia	Ignatius Joshua Kandou  Indonesia	Milad Mardas Cheun  Cambodia
			Chu Đức Thịnh  Vietnam
−84 kg	Đỗ Thành Nhân  Vietnam	Thodny Phingsamphan  Laos	Ivan Christopher Agustin  Philippines
			Teerawat Pongsai  Thailand
Team	Malaysia Geerijaieswaran Pillai Sivanesan Kathish S. Gnanasekaran Kueggen Vijaya Kumar M. Arif Afifuddin Ab Malik Prem Kumar Selvam Sharmendran Raghonathan Sureeya Sankar Hari Sankar	Indonesia Ari Saputra Claudio Fernando Nenobesi Ignatius Joshua Kandou Nur Halim Arlendi Sandi Firmansah Tebing Hutapea	Thailand Teerapat Kanabkaew Siwakon Muekthong Chaiwat Phiandee Chalermpon Piwlaaiad Teerawat Pongsai Puris Saiyasombat Worakan Soda
			Vietnam Chu Đức Thịnh Đặng Hồng Sơn Đỗ Thành Nhân Nguyễn Văn Nhật Phạm Minh Nhựt Trần Lê Tấn Đạt Vũ Anh Quân

Event	Gold	Silver	Bronze
−50 kg	Shahmalarani Chandran  Malaysia	Chanyanut Chippensuk  Thailand	Sharon Verlina Ririhena  Indonesia
			Đinh Thị Hương  Vietnam
−55 kg	Cok Istri Agung Sanistyarani  Indonesia	Pensiput Namkhao  Thailand	Toukta Moukdavong  Laos
			Hoàng Thị Mỹ Tâm  Vietnam
−61 kg	Nguyễn Thị Ngoan  Vietnam	Devina Dea  Indonesia	Jamie Lim  Philippines
			Arm Sukkiaw  Thailand
−68 kg	Hồ Thị Thu Hiền  Vietnam	Ceyco Georgia Zefanya  Indonesia	Amirah Syahirah Azlan  Malaysia
			Remon Misu  Philippines
+68 kg	Bùi Thị Thảo  Vietnam	Dessyinta Rakawuni Banurea  Indonesia	Soudanihen Vann  Cambodia
			Kewalin Songklin  Thailand
Team	Vietnam Hồ Thị Thu Hiền Hoàng Thị Mỹ Tâm Nguyễn Thị Ngoan Trang Cẩm Lành	Indonesia Ceyco Georgia Zefanya Cok Istri Agung Sanistyarani Dessyinta Rakawuni Banurea Devina Dea Sharon Verlina Ririhena	Malaysia Madhuri Poovanesan Mathivani Murugeesan Preyancli Santhiran Siti Nur Azwani Nor Azli
			Philippines Jamie Lim Mae Soriano Eso Remon Misu Junna Tsukii