Karamo is filmed at the Rich Forum in Stamford, Connecticut, which is alternatively known as the Stamford Media Center.[2] The program is generally a successor to Maury, on which Brown was a frequent guest host[3] and whose production team moved over to Karamo.[4] The program had achieved 90 percent national clearance by April 2022.[3] Though it films in the same studio as The Jerry Springer Show, Brown has stated that he seeks more resolutions to conflicts than Springer or Maury Povich did, telling Los Angeles magazine that there would be "no baby mama stuff",[5] and compared his take on the daytime talk genre to the 2018 reboot of Queer Eye, on which he features.[2] He also has cited his experience in social services as part of the background he brings to the show.[6] A feature in The Washington Post noted that the new daytime talk shows for the 2022–23 season—Karamo, Sherri, and The Jennifer Hudson Show—all represented a return to a pre-tabloid, pre-Springer community focus and tone.[7]
In March 2023, NBCUniversal renewed the program for a second season; the program was cleared in 85 percent of the United States at that time.[8] A third season was announced in March 2024.[9]
The program had a reported 600,000 daily viewers by March 2023, an 18-percent increase from the start of the television season, though this was still well behind the 1.7 million viewers tuning in to Maury daily as of 2020, as well as such programs as The Drew Barrymore Show and Sherri.[2] NBCUniversal reported growth of 20 percent in total viewers for the second season.[9]