Search Results: KV1.3
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KCNA3
Kamis, 2025-09-25 05:35:28Potassium voltage-gated channel, shaker-related subfamily, member 3, also known as KCNA3 or Kv1.3, is a protein that in humans is encoded by the KCNA3 gene....
Click to read more »Clofazimine
Jumat, 2026-05-22 09:26:47diabetes. Because the Kv1.3-high effector memory T cells (TEM) are actively involved in the development of these diseases, and Kv1.3 activity is essential...
Click to read more »Kv1.1
Jumat, 2026-04-24 00:53:31Potassium voltage-gated channel subfamily A member 1 also known as Kv1.1 is a shaker related voltage-gated potassium channel that in humans is encoded...
Click to read more »Stichodactyla toxin
Rabu, 2026-08-12 00:35:48mouse Kv1.3 external vestibule (corresponds to Asp433 in human Kv1.3). Several ShK analogues have been generated to enhance specificity for the Kv1.3 channel...
Click to read more »Pi5
Rabu, 2025-06-11 06:27:33the African emperor scorpion Pandinus imperator. Pi5 inhibits human Kv1.2 and Kv1.3 channels as well as Drosophila Shaker B potassium channels. Pi5 is...
Click to read more »Pandinus imperator (Pi3) toxin
Selasa, 2025-06-24 09:53:41potassium channel, Kv1.3 and is closely related to another peptide found in the venom, Pi2. Pi3 toxin stands for Pandinus imperator-3 toxin. It is also...
Click to read more »Hg1 (toxin)
Rabu, 2026-03-18 11:41:17it selectively inhibits the potassium channel Kv1.3 and, with a lower affinity, channels Kv1.1 and Kv1.2. The Hg1 toxin is named after the Mexican scorpion...
Click to read more »Human uses of scorpions
Kamis, 2025-11-06 00:47:13peptides. An important physiological role of the KCNA3 channel, also known as KV1.3, is to help maintain large electrical gradients for the sustained transport...
Click to read more »Ts15
Senin, 2021-10-25 03:01:35It targets voltage-gated potassium channels, primarily the subtypes Kv1.2 and Kv1.3. Ts15 can be isolated from the venom of Tityus serrulatus, otherwise...
Click to read more »BmP02
Sabtu, 2026-06-13 05:24:21martensi Karsch (BmK) scorpion. The toxin acts on potassium channels, blocking Kv1.3 and slowing the deactivation of Kv4.2. BmP02 is not toxic to humans or mice...
Click to read more »BF9
Sabtu, 2025-05-24 01:45:19inhibit both serine proteases and potassium channels (more specifically the Kv1.3 channel). Venom basic protease inhibitor IX, also named BF9, is derived...
Click to read more »Ctri9577
Senin, 2026-06-22 19:18:15a potent blocker of the voltage-gated potassium channel Kv1.3, and a gating modifier of Kv4.3 channels. The Ctri9577 toxin is a component of the venom...
Click to read more »LmKTT-1a
Minggu, 2025-09-28 07:24:22toxin, it both inhibits trypsin activity and blocks Kv1 channels with a weak selectivity towards Kv1.3 channels. The LmKTT-1a toxin was first identified...
Click to read more »Kaliotoxin
Rabu, 2026-07-29 09:26:22Kaliotoxin (KTX) inhibits potassium flux through the Kv1.3 voltage-gated potassium channel and calcium-activated potassium channels by physically blocking...
Click to read more »LmKTx10
Selasa, 2026-01-27 05:33:17channels of the family Kv1. It has a higher selectivity for the Kv1.3 potassium channel (KCNA3), compared to other channels in the Kv1 family. The Name LmKTx10...
Click to read more »Hefutoxin
Jumat, 2026-04-10 22:21:45unique structure. It blocks the potassium channels Kv1.2 and Kv1.3 and slows the activation of Kv1.3. The kappa- Hefutoxin 1 and 2 (κ- hefutoxin1/2) are...
Click to read more »Gary Desir
Kamis, 2025-10-16 00:54:30Li, Yanling Wu, and Gary V. Desir. The voltage-gated potassium channel Kv1.3 regulates peripheral insulin sensitivity Jianchao Xu, Peili Wang, Yanyan...
Click to read more »Spinoxin
Minggu, 2026-02-01 09:07:38effects by inhibiting voltage-gated potassium channels, specifically Kv1.2 and Kv1.3. Spinoxin is isolated from the venom of the Malaysian black scorpion...
Click to read more »Margatoxin
Sabtu, 2025-06-14 04:28:55Margatoxin (MgTX) is a peptide that selectively inhibits Kv1.3 voltage-dependent potassium channels. It is found in the venom of Centruroides margaritatus...
Click to read more »Cm28
Kamis, 2025-10-16 01:38:59margaritatus, selectively blocks voltage-gated potassium channels KV1.2 and KV1.3 with high affinity. It also suppresses the activation of human CD4+...
Click to read more »Psora-4
Senin, 2026-06-08 16:39:08Psora-4 is an experimental drug that acts as a selective inhibitor of the Kv1.3 potassium channel. It has immunomodulatory effects, suppressing the proliferation...
Click to read more »ImKTX58
Minggu, 2025-11-16 18:17:52the lesser brown scorpion). It is known for its selective inhibition of Kv1.3 channels, on which it acts as a pore-blocker. The name of ImKTX58 stems...
Click to read more »Hongotoxin
Kamis, 2025-07-17 00:33:35Shaker-type (Kv1) K+ channels. HgTX1 shows high affinity with Kv1.1, Kv1.2, Kv1.3 voltage-gated potassium channels, but much lower affinity with Kv1.6 (see...
Click to read more »OdK2
Sabtu, 2026-05-16 01:51:56α-KTx family, and selectively blocks the voltage-gated potassium channel Kv1.3 (KCNA3). OdK2 is an acronym for the species of origin, the substrate of...
Click to read more »MeuKTX
Minggu, 2021-10-24 04:13:53eupeus. This short-chain peptide blocks potassium channels, such as Kv1.1, Kv1.2 and Kv1.3. MeuKTX is a neurotoxin found in the venom of the scorpion Mesobuthus...
Click to read more »BscTx3
Senin, 2024-12-23 07:08:30potassium channels Kv1.1, Kv1.2, Kv1.3, Kv1.6 as well as Drosophila Shaker IR channels. The IC50 values for these channels are 172.59 nM for Kv1.2/KCNA2, 2245...
Click to read more »Cvill7
Sabtu, 2025-12-20 15:47:02toxins. Particularly, Cvill7 exerts a high affinity for Kv1.2, with weaker effects on Kv1.1 and Kv1.3. | colspan="2" |Cvill7 |- |Superfamily |Scorpion toxins...
Click to read more »Hemitoxin
Kamis, 2023-11-02 21:24:25Iranian scorpion Hemiscorpius lepturus, which reversibly blocks Kv1.1, Kv1.2 and Kv1.3 voltage-gated K+ channels. HTX is a neurotoxin derived from the...
Click to read more »HsTx1
Minggu, 2025-08-31 14:13:54the rat Kv1.3 voltage-gated potassium channel. HsTx1 stands for Heterometrus spinifer Toxin 1. The systematic name for this toxin is α-KTx 6.3. HsTx1 is...
Click to read more »Tst26
Selasa, 2025-05-27 12:45:03stigmurus, a species of Brazilian scorpion. Tst26 selectively blocks Kv1.2 and Kv1.3 channels. Tst26 is named after the species it was discovered from and...
Click to read more »BmK NSPK
Kamis, 2024-06-06 07:45:16with BmKTX (Buthus martensii kaliotoxin), which is a previously discovered Kv1.3 channel blocker, BmK NSPK showed 79% sequence homology. Furthermore, BmKTX...
Click to read more »OSK3
Sabtu, 2025-10-11 01:35:39subfamily and targets the voltage-gated potassium channels KCNA2 (Kv1.2), and KCNA3 (Kv1.3). OSK3 is secreted from the venom gland of Orthochirus scrobiculosus...
Click to read more »Pandinus imperator toxin
Kamis, 2025-09-18 03:18:17voltage-gated potassium channel Kv1.2. at low concentrations (IC50 8.0 ± 5 pM). No significant effects have been observed on Kv1.1 and Kv1.3 channels at concentrations...
Click to read more »Anuroctoxin
Senin, 2024-12-23 07:08:38of potassium channel acting peptides. It is a high-affinity blocker of Kv1.3 channels. Anuroctoxin is a peptide which is derived from the scorpion Anuroctonus...
Click to read more »BmKTX
Senin, 2025-11-03 11:14:00BmKTX (alpha-KTx 3.6) is a scorpion neurotoxin which blocks the voltage gated potassium channel Kv1.3. The name BmK part of the toxin is derived from the...
Click to read more »Psoralen
Jumat, 2026-07-24 08:15:56Heike Wulff (November 2005). "Design of PAP-1, a selective small molecule Kv1.3 blocker, for the suppression of effector memory T cells in autoimmune diseases"...
Click to read more »Lesional demyelinations of the central nervous system
Kamis, 2026-08-13 08:00:57Wulff H, Calabresi PA, Allie R, et al. (June 2003). "The voltage-gated Kv1.3 K(+) channel in effector memory T cells as new target for MS". J. Clin....
Click to read more »BgK
Senin, 2025-11-17 22:15:10BgK blocks the Kv1.1, Kv1.2, and Kv1.3 channels with similar affinities. IC50 is 6 nM for Kv1.1, 15 nM for Kv1.2, and 10 nM for Kv1.3. Meanwhile, tests...
Click to read more »Parabutoxin
Sabtu, 2025-06-21 06:28:29Shaker-related voltage-gated potassium channels members 1,2 and 3 (Kv1.1, Kv1.2 and Kv1.3 channels). These channels have different functions that include...
Click to read more »Zoltán Takács (toxinologist)
Rabu, 2025-10-01 20:38:22Suarez-Kurtz G, Koide S, Goldstein SA (2009). "A designer ligand specific for Kv1.3 channels from a scorpion neurotoxin-based library". Proceedings of the National...
Click to read more »Olivierus martensii
Selasa, 2026-04-21 05:51:36used in anticancer treatments. BmP02 acts on potassium channels, blocking Kv1.3 and slowing the deactivation of Kv4.2. BmP02 is not toxic to humans or mice...
Click to read more »Tyrosin-protein kinase Lck
Kamis, 2026-04-16 03:22:52large tumor suppressor binds to p56lck tyrosine kinase and Shaker type Kv1.3 potassium channel in T lymphocytes". The Journal of Biological Chemistry...
Click to read more »Developmental bioelectricity
Kamis, 2026-08-13 03:33:23PMID 26216856. Duque, A.; Gazula, V. R.; Kaczmarek, L. K. (2013). "Expression of Kv1.3 potassium channels regulates density of cortical interneurons". Developmental...
Click to read more »KCNA5
Rabu, 2025-07-23 22:29:50voltage-gated channel, shaker-related subfamily, member 5, also known as KCNA5 or Kv1.5, is a protein that in humans is encoded by the KCNA5 gene. Potassium channels...
Click to read more »KCNA4
Selasa, 2025-07-15 11:20:40Potassium voltage-gated channel subfamily A member 4 also known as Kv1.4 is a protein that in humans is encoded by the KCNA4 gene. It contributes to the...
Click to read more »Multiple sclerosis drug pipeline
Selasa, 2026-03-31 11:28:41suppress myelin-reactive effector memory T cells by blocking voltage-gated Kv1.3 channels in these cells. hydralazine: Due to its ability to damage myelin...
Click to read more »ImKTx88
Sabtu, 2026-03-28 21:50:53ImKTx88 is a selective inhibitor of the Kv1 ion channel family that can be isolated from the venom of the Isometrus maculatus (lesser brown scorpion)...
Click to read more »Markus Sperandio
Senin, 2026-05-25 00:33:43Deutsche Forschungsgemeinschaft. Retrieved 2026-05-05. "C2: The role of KV1.3 on Ca2+ signalling and neutrophil effector functions". Website of the Transregio...
Click to read more »Mesobuthus eupeus
Selasa, 2026-05-19 01:05:49M. martensii, potently inhibits rKv1.1, rKv1.2 and hKv1.3 channels but does not affect rKv1.4, rKv1.5, hKv3.1, rKv4.3, and hERG channels even at high concentrations...
Click to read more »Maurotoxin
Sabtu, 2026-04-18 16:32:34channels (IK) Several types of voltage-gated potassium channels (Kv1.1, Kv1.2, Kv1.3 and shaker B) The structural and pharmacological features of MTX...
Click to read more »Christine Beeton
Kamis, 2026-03-26 02:19:00the first person able to show the significant benefits of blocking Kv1.1 and Kv1.3 channels with kaliotoxin - a component of scorpion venom - as a preventative...
Click to read more »List of MeSH codes (D12.776.543)
Jumat, 2025-08-15 03:47:17311 – kv1.1 potassium channel MeSH D12.776.543.550.425.750.900.124.342 – kv1.2 potassium channel MeSH D12.776.543.550.425.750.900.124.358 – kv1.3 potassium...
Click to read more »Scaffold protein
Selasa, 2026-03-24 06:08:23Large Tumor Suppressor Binds to p56 lck Tyrosine Kinase and Shaker Type Kv1.3 Potassium Channel in T Lymphocytes". Journal of Biological Chemistry. 272...
Click to read more »Voltage-gated potassium channel
Sabtu, 2026-06-20 02:14:05non-inactivating Kvα1.x - Shaker-related: Kv1.1 (KCNA1), Kv1.2 (KCNA2), Kv1.3 (KCNA3), Kv1.5 (KCNA5), Kv1.6 (KCNA6), Kv1.7 (KCNA7), Kv1.8 (KCNA10) Kvα2.x - Shab-related:...
Click to read more »Ssm spooky toxin
Minggu, 2026-05-31 09:16:11(KV7.1, KV7.2, KV7.4, and KV7.5) but it has also been found to inhibit KV1.3 (and the Drosophila homolog shaker), KV2.1 (KCNB1) and KV4 (and its Drosophila...
Click to read more »Calyx of Held
Minggu, 2026-07-26 08:20:57present: Kv1.1, Kv1.2, Kv1.3, and Kv7.5. Kv1.1 and Kv1.2 are located in the transition zone between the axon and the terminal, while Kv1.3 Kv7.5 are...
Click to read more »KCNA2
Senin, 2025-11-17 23:03:52Potassium voltage-gated channel subfamily A member 2 also known as Kv1.2 is a protein that in humans is encoded by the KCNA2 gene. Potassium channels...
Click to read more »Jonathan Baell
Rabu, 2026-02-11 01:34:29"Khellinone Derivatives as Blockers of the Voltage-Gated Potassium Channel Kv1.3: Synthesis and Immunosuppressive Activity". Journal of Medicinal Chemistry...
Click to read more »DLG1
Sabtu, 2025-12-06 04:34:13large tumor suppressor binds to p56lck tyrosine kinase and Shaker type Kv1.3 potassium channel in T lymphocytes". The Journal of Biological Chemistry...
Click to read more »SGK1
Selasa, 2026-02-24 06:07:42and epithelial K+ channels KCNE1/KCNQ1 Voltage-gated K+ channels Kv1.3, Kv1.5, and Kv4.3 Glutamate Receptors The following carriers and pumps are influenced...
Click to read more »List of MeSH codes (D12.776.157)
Jumat, 2025-08-15 03:43:00124 – kv1.1 potassium channel MeSH D12.776.157.530.400.600.900.500.186 – kv1.2 potassium channel MeSH D12.776.157.530.400.600.900.500.217 – kv1.3 potassium...
Click to read more »KCNA6
Sabtu, 2025-07-19 03:39:09Potassium voltage-gated channel subfamily A member 6 also known as Kv1.6 is a protein that in humans is encoded by the KCNA6 gene. The protein encoded...
Click to read more »Stichodactyla helianthus
Selasa, 2026-06-23 12:22:19Specific Kv1.3 Channel Inhibitor That Suppresses T Cell Mediators of Autoimmune Disease". The Journal of Pharmacology and Experimental Therapeutics. 342 (3):...
Click to read more »Potassium channel blocker
Selasa, 2026-06-23 13:40:46voltage-gated Kv2.1 potassium channel currents. a very potent inhibitor of the rat Kv1.3 voltage-gated potassium channel Voigt N, Dobrev D (2016). "Atrial-Selective...
Click to read more »APEKTx1
Sabtu, 2025-08-30 20:13:03channel Kv1.1 with no effect on other tested potassium channels (Kv1.2, Kv1.3, Kv1.4, Kv1.5, Kv1.6, Shaker IR, Kv2.1, Kv3.1, Kv4.2 and Kv4.3). APEKTx1...
Click to read more »Cation channel superfamily
Kamis, 2025-10-02 00:53:46RYR3 Kvα1.x - Shaker-related: Kv1.1 (KCNA1), Kv1.2 (KCNA2), Kv1.3 (KCNA3), Kv1.5 (KCNA5), Kv1.6 (KCNA6), Kv1.7 (KCNA7), Kv1.8 (KCNA10) Kvα2.x - Shab-related:...
Click to read more »KCNE2
Selasa, 2025-09-16 05:02:47forms complexes there with the voltage-gated potassium channel α subunit, Kv1.3. In addition, KCNE2 forms reciprocally regulating tripartite complexes in...
Click to read more »Gambierol
Minggu, 2025-08-31 14:48:03especially Kv1.1-1.5 channels and the Kv3.1 channel. Kv1.1-1.5 channels are responsible for repolarization of the membrane potential. The Kv1.3 channel however...
Click to read more »CboK7
Kamis, 2025-10-16 01:38:43bonito. It blocks voltage-gated K+ channels, with the highest affinity for Kv1.2 channels. This toxin is known by two names: CboK7 and α-KTx 2.24. The name...
Click to read more »Episodic ataxia
Selasa, 2025-07-15 11:08:14encodes the voltage-gated potassium channel KV1.1, are responsible for this subtype of episodic ataxia. KV1.1 is expressed heavily in basket cells and...
Click to read more »Ts8
Sabtu, 2026-01-31 05:25:58in three forms, of which Ts8-FragII has a small inhibitory effect on the Kv1.3 channel. The inhibition caused by the neurotoxin Ts8 on Kv4.2 channels increases...
Click to read more »Heteroscodratoxin-1
Rabu, 2025-05-28 20:36:53and KV3.4) or delayed rectifier potassium channels (KV1.1, KV1.2, KV1.3, KV1.5, KV1.6, KV1.2/ KV1.5, or KVLQT1), or on sodium and calcium channels has...
Click to read more »SHC3
Kamis, 2025-12-18 14:33:59proteins differentially modulate the phosphorylation and biophysics of Kv1.3 ion channel by SRC kinase". The Journal of Biological Chemistry. 277 (15):...
Click to read more »Ramesses VII
Sabtu, 2026-06-20 14:28:27was buried in Tomb KV1 upon his death. Finely carved wall reliefs in Ramesses VII's KV1 tomb The Tomb Corridor of Ramesses VII's KV1 tomb His mummy has...
Click to read more »DUSP3
Kamis, 2025-07-17 00:10:23Swanson R (Feb 1995). "Confirmation of the assignment of the gene encoding Kv1.3, a voltage-gated potassium channel (KCNA3) to the proximal short arm of...
Click to read more »KCNAB1
Sabtu, 2025-07-19 13:14:43large tumor suppressor binds to p56lck tyrosine kinase and Shaker type Kv1.3 potassium channel in T lymphocytes". J. Biol. Chem. 272 (43): 26899–904...
Click to read more »KCNE4
Senin, 2025-09-29 15:45:50strongly inhibits Kv1.1 and Kv1.3 channels when co-expressed in HEK cells and in Xenopus laevis oocytes, while leaving Kv1.2 and Kv1.4 currents unaffected...
Click to read more »Cobatoxin
Sabtu, 2025-09-13 05:11:25(KTx), which consists of 3 families; α, β, and γ. These 3 families differ in structure. Cobatoxin 1 and 2 both block the Kv1.1 K+-channels in mice and...
Click to read more »Jackson King V
Sabtu, 2025-06-14 00:45:53but with dot inlays, no binding, and rosewood fretboard. KV1(Artist Signature Series) The KV1 is a Dave Mustaine signature model and is the first commercially-sold...
Click to read more »Dave Mustaine
Sabtu, 2026-08-08 21:53:56meaning it had two of the longer fins from the RR). The reshaped Mustaine KV1 model had slightly shorter fins, Kahler bridge and Seymour Duncan TB-5 bridge...
Click to read more »Twentieth Dynasty of Egypt
Selasa, 2026-08-04 21:13:55discovery by Howard Carter in 1922. Ramesses VII's only monument is his tomb, KV1.[citation needed] Almost nothing is known about Ramesses VIII's reign, which...
Click to read more »Valley of the Kings
Jumat, 2026-08-07 04:26:30signs for the tombs, providing information and plans of the open tombs. KV1 KV2 KV3 KV4 KV5 KV6 KV7 KV8 KV9 KV10 KV11 KV12 KV13 KV14 KV15 KV16 KV17 KV18...
Click to read more »List of burials in the Valley of the Kings
Kamis, 2026-07-30 19:13:46also used to designate tombs located in the West Valley (of the Kings). KV1 KV2 KV3 KV4 KV5 KV6 KV7 KV8 KV9 KV10 KV11 KV12 KV13 KV14 KV15 KV16 KV17 KV18...
Click to read more »Butantoxin
Kamis, 2025-09-18 20:47:06blocks the voltage-gated K+ channels Shaker B and Kv1.2, and the Ca2+-activated K+ channels KCa 1.1 and KCa 3.1. Butantoxin is one of multiple toxins isolated...
Click to read more »Kalicludine
Sabtu, 2025-12-27 20:13:58Kalicludine (AsKC) is a blocker of the voltage-dependent potassium channel Kv1.2 found in the snakeslocks anemone Anemonia viridis (Anemonia sulcata), which...
Click to read more »BrMT
Sabtu, 2024-11-23 11:36:04The disulfide-linked dimer of BrMT possesses inhibitory effects on the Kv1 and Kv4 families of voltage-gated potassium channels. BrMT was first isolated...
Click to read more »Endocannabinoid system
Sabtu, 2026-06-27 11:21:12Immunohistochemistry experiments demonstrated that CB1 is co-localized with GIRK and Kv1.4 potassium channels, suggesting that these two may interact in physiological...
Click to read more »XEN-D0101
Selasa, 2026-06-30 10:15:40XEN-D0101 is a selective antagonist of the voltage-gated potassium channel Kv1.5. Atrial fibrillation is the main focus of Xention’s drug development, as...
Click to read more »KCNA10
Sabtu, 2023-03-04 03:33:37Potassium voltage-gated channel subfamily A member 10 also known as Kv1.8 is a protein that in humans is encoded by the KCNA10 gene. The protein encoded...
Click to read more »Sisu Nasu
Kamis, 2024-11-14 01:48:5312 in tail unit. NA-111GT A signal station version. NA-120 GT NA-120 GT KV1 Armoured variant used in UN-operations. NA-122 A version that carries a 120 mm...
Click to read more »Essential fatty acid
Senin, 2025-12-29 04:01:081994). "External blockade of the major cardiac delayed-rectifier K+ channel (Kv1.5) by polyunsaturated fatty acids". Proceedings of the National Academy of...
Click to read more »Amitriptyline
Selasa, 2026-08-11 22:24:17(3): 1015–1023. doi:10.1016/S0022-3565(24)35384-4. PMID 10688618. Punke MA, Friederich P (May 2007). "Amitriptyline is a potent blocker of human Kv1.1...
Click to read more »Kappa-KTx2.5
Senin, 2026-05-11 15:24:44residue of κ-KTx2.5 interacts with aspartic acid-348 (D348) of Kv1.2 at a distance of 3.7 Å, affecting only one subunit. Lysine-23 (K23) in the toxin likely...
Click to read more »Kendriya Vidyalaya No. 2, Vizag
Sabtu, 2026-02-21 08:59:53and one Navy Children School in the Naval Campus. The other three being KV1, NSB; KV Malkapuram; NCS, NSB, Vizag. The school has a fairly big campus...
Click to read more »Team Secret
Rabu, 2026-07-29 09:52:44September 19 math was removed from the starting lineup. October 8 Danilo "kv1" Michelini joined. On January 8, 2024, Team Secret announced the formation...
Click to read more »Sigma-1 receptor
Selasa, 2026-08-11 19:23:23has been shown to appear in a complex with voltage gated K+ channels (Kv1.4 and Kv1.5), leading to the idea that σ1 receptors are auxiliary subunits. σ1...
Click to read more »Repolarization
Senin, 2026-04-27 05:53:59membrane to re-establish the resting potential. The four types are Kv1, Kv2, Kv3 and Kv4. The Kv1 channel primarily influences the repolarization of the axon...
Click to read more »Activation
Jumat, 2026-01-30 01:25:55Antonella; Rolland, Jean-Francois; Pessia, Mauro; Imbrici, Paola (2020-04-22). "Kv1.1 Channelopathies: Pathophysiological Mechanisms and Therapeutic Approaches"...
Click to read more »Morvan's syndrome
Kamis, 2026-08-13 03:34:16neuromyotonia. It is believed that antibodies to the Shaker-type K+ channels (the Kv1 family) are the type of potassium channel most strongly associated with acquired...
Click to read more »KCNA7
Minggu, 2022-04-17 10:12:23Potassium voltage-gated channel subfamily A member 7 also known as Kv1.7 is a protein that in humans is encoded by the KCNA7 gene. The protein encoded...
Click to read more »Discovery of the tomb of Tutankhamun
Minggu, 2026-07-12 23:31:2090–91. Carter & Mace 2003, pp. 91–95. Hoving 1978, p. 87. Frayling 1992, pp. 3–4. Carter & Mace 2003, pp. 95–96. Frayling 1992, pp. 4–5. Reeves 1990, pp...
Click to read more »Middle Khmer
Minggu, 2026-06-28 01:12:08pre-Angkor and modern Khmer" (PDF). Pacific Linguistics. 42 (19): 19–38. Retrieved 3 January 2016. Lewitz, Saveros (1967). "La toponymie khmère". Bulletin de l'École...
Click to read more »Kaamelott: The First Chapter
Rabu, 2026-08-05 06:13:16"KAAMELOTT - PREMIER VOLET sortira au cinéma le 21 juillet.#KaamelottLeFilm #KV1" (Tweet) – via Twitter. "Kaamelott : Premier Volet sortira en salle le 21...
Click to read more »GABRA3
Rabu, 2025-10-22 11:33:37alter chloride permeability of the GABA receptor. At the time of discovery, Kv1.1 mRNA was the only previously known mammalian coding site containing both...
Click to read more »Palmitoyl acyltransferase
Kamis, 2025-02-13 07:46:34receptor subunit GluR1 and GluR2, GABAA receptor gamma2 subunit, aquaporin, KV1.1, rhodopsin, beta2-adrenergic receptor, and PSD-95. https://swisspalm.org/enzymes...
Click to read more »MCD peptide
Jumat, 2024-08-16 16:43:38characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines". Mol Pharmacol....
Click to read more »Panchkula
Senin, 2026-08-10 02:46:05School, Morni Rd Jainendra Public School, Sector 1 Kendriya Vidyalaya No. 1 (KV1), Chandimandir Cantonment Kendriya Vidyalaya No. 2 (KV2), Chandimandir Cantonment...
Click to read more »4-Aminopyridine
Kamis, 2026-07-23 07:57:08biophysics.[citation needed] It is a relatively selective blocker of members of Kv1 (Shaker, KCNA) family of voltage-activated K+ channels. However, 4-AP has...
Click to read more »Rongorongo text K
Senin, 2024-10-28 19:45:14tablets. There are five lines of glyphs on the recto, a transitional line (Kv1) along the edge, and four lines (Kv2-5) on the verso proper. The first and...
Click to read more »Heteropodatoxin
Rabu, 2023-07-19 23:33:55heteropodatoxin-2 blocks the potassium channels Kv4.1, Kv4.2 and Kv4.3, but not Kv1.4, Kv2.1, or Kv3.4. Heterpodatoxin-2 most likely acts as a gating modifier...
Click to read more »Pandinotoxin
Sabtu, 2025-06-14 04:28:26channels of the subfamily A member 2 (Kv1.2/KCNA2) [1] and they can reversibly block the shaker B potassium-channels (Kv1.1 sub-family). The residue K27, a...
Click to read more »Cardiac transient outward potassium current
Sabtu, 2025-11-01 08:44:58needed] The Ito1 is generated by voltage-gated K+ channels Kv1.4, Kv4.2, and (especially) Kv4.3; these channels undergo ball-and-chain inactivation to terminate...
Click to read more »Anti-VGKC-complex encephalitis
Minggu, 2026-05-17 22:07:08detected with the radioimmunoprecipitation assay, only 3 (3%) had antibodies towards the Kv1 subunit of the VGKC channel, 55 (57%) had antibodies against...
Click to read more »GJC3
Sabtu, 2023-03-04 06:49:56In both PNS and CNS myelinated axons, Cx29 is precisely colocalized with Kv1.2 voltage-gated K+ channels, where both proteins are concentrated in the...
Click to read more »Cadherin-2
Selasa, 2026-08-11 17:31:28that the arrhythmias were likely due to ion channel remodeling and aberrant Kv1.5 channel function. These animals showed a prolonged action potential duration...
Click to read more »Cortactin
Jumat, 2025-10-31 13:40:40E, Cachero TG, Morielli AD (October 2002). "Tyrosine phosphorylation of Kv1.2 modulates its interaction with the actin-binding protein cortactin". J...
Click to read more »Quinidine
Selasa, 2026-06-02 14:49:48agent. Quinidine also blocks certain voltage-gated potassium channels (e.g., Kv1.4, Kv4.2, hERG, among others), acts as an antimuscarinic and alpha-1 blocker...
Click to read more »List of unnumbered trans-Neptunian objects
Jumat, 2026-07-03 08:23:58Spacewatch (691) 76 centaur 35.8 0.62 11 13.6 58.0 albedo: 0.058 MPC · JPL 1996 KV1 21 May 1996 C. A. Trujillo, D. C. Jewitt, J. X. Luu (568) 164 cubewano (hot)...
Click to read more »KCNAB2
Kamis, 2025-07-17 00:42:22Coleman SK, Newcombe J, Pryke J, Dolly JO (Aug 1999). "Subunit composition of Kv1 channels in human CNS". J. Neurochem. 73 (2): 849–58. doi:10.1046/j.1471-4159...
Click to read more »Jackson Y2KV
Sabtu, 2026-06-06 09:35:39Retrieved 2009-12-21. Jackson Catalog 2001. Tuners are arranged in the classic 3-a side style instead of the usual six a side. These two differences combined...
Click to read more »List of unnumbered minor planets: 1996
Senin, 2026-07-27 20:52:21510 m single 66 days 18 Jul 1996 80 Disc.: NEAT/GEODSS MPC · JPL 2 1996 KV1 TNO 7.3 178 km multiple 1996–2016 29 May 2016 27 Disc.: Mauna Kea Obs. LoUTNOs...
Click to read more »Neuroprotection
Kamis, 2026-08-13 00:13:22fluid of sporadic amyotrophic lateral sclerosis patients alters Nav1.6 and Kv1.6 channel expression in rat spinal motor neurons". Brain Research. 1255:...
Click to read more »Saak Ovsepian
Jumat, 2026-06-26 05:07:24Valerie B O'Leary, Christian Leibold, J Oliver Dolly. "Distinctive role of KV1.1 subunit in the biology and functions of low threshold K+ channels with...
Click to read more »List of minor planets: 892001–893000
Rabu, 2026-07-01 02:48:00JN26 — May 14, 2015 Haleakala Pan-STARRS 1 · 2.4 km MPC · JPL 892395 2015 KV1 — April 10, 2015 Haleakala Pan-STARRS 1 · 860 m MPC · JPL 892396 2015 KH10...
Click to read more »Sulfatide
Kamis, 2026-02-19 23:27:35number of clusters of sodium channels at the nodes of Ranvier. Additionally, Kv1.2 channels are moved from the paranodal position to the juxtaparanodal position...
Click to read more »Potassium channel
Sabtu, 2026-06-20 09:34:29Life Sciences. Vol. 16. Springer. pp. 325–347. doi:10.1007/978-3-319-21756-7_9. ISBN 978-3-319-21755-0. PMID 26860305. indirectly cited from reference number...
Click to read more »List of cis-regulatory RNA elements
Senin, 2024-10-07 04:32:38(PIE) UnaL2 LINE 3′ element Vimentin 3′ UTR protein-binding region Voltage-gated potassium-channel Kv1.4 IRES Wingless localisation element 3 (WLE3) xerDC...
Click to read more »GRIA3
Senin, 2025-10-27 23:16:02structure is related to that found in K+ channels (e.g., human Kv1.1 channel). The human Kv1.1 channel pre mRNA is also subject to A to I RNA editing. The...
Click to read more »Pharmacodynamics of spironolactone
Selasa, 2025-12-23 06:16:24(2005). "Spironolactone and its main metabolite canrenoic acid block hKv1.5, Kv4.3 and Kv7.1+minK channels". British Journal of Pharmacology. 146 (1): 146–161...
Click to read more »DLG4
Kamis, 2025-07-31 20:47:58D (November 2002). "N-terminal PDZ-binding domain in Kv1 potassium channels". FEBS Lett. 531 (3): 529–37. Bibcode:2002FEBSL.531..529E. doi:10.1016/S0014-5793(02)03572-X...
Click to read more »HgeTx1
Senin, 2024-12-23 07:50:44"Contribution of the functional dyad of animal toxins acting on voltage-gated Kv1-type channels". J Pept Sci. 11 (2): 65–8. doi:10.1002/psc.630. PMID 15635666...
Click to read more »Tityustoxin
Jumat, 2026-05-22 20:14:34peptide toxin, interacts with the alpha-dendrotoxin binding site on the cloned Kv1.2 K+ channel". Molecular Pharmacology. 44 (2): 430–436. doi:10.1016/S0026-895X(25)13197-0...
Click to read more »GRIA2
Senin, 2025-10-27 23:17:06related to that found in K+ channels, such as the human Kv1.1 channel. The pre-mRNA of the human Kv1.1 channel is also subject to A-to-I RNA editing. Glutamate...
Click to read more »KCNA2-related disorders
Kamis, 2026-04-09 18:11:06KCNA2-related disorders are caused by mutations to the Kv1.2 channels encoded by the KCNA2 gene. These neurological disorders are associated with a spectrum...
Click to read more »LGI1
Jumat, 2026-06-05 08:50:15Peles E, Buckley C, Lang B, Vincent A (September 2010). "Antibodies to Kv1 potassium channel-complex proteins leucine-rich, glioma inactivated 1 protein...
Click to read more »Genetically encoded voltage indicator
Selasa, 2026-08-11 23:14:36fluorescent protein FRET pair, e.g. VSFP1, (2) Single opsin GEVIs, e.g. Arch, (3) Opsin-FP FRET pair GEVIs, e.g. MacQ-mCitrine, (4) single FP with special...
Click to read more »Index of biophysics articles
Selasa, 2025-09-02 20:37:54KCNT2 KCNV1 KCNV2 Kenneth Stewart Cole Kim Sung-Hou Kir2.1 Kir2.6 Kir6.2 Kv1.1 KvLQT1 KvLQT2 KvLQT3 L-type calcium channel Lamellar structure Lamellipodium...
Click to read more »KCNQ1
Jumat, 2026-07-24 04:12:00Norwegian perspective". Am. J. Med. Genet. 89 (3): 137–146. doi:10.1002/(SICI)1096-8628(19990924)89:3<137::AID-AJMG4>3.0.CO;2-C. PMID 10704188. Gutman GA, Chandy...
Click to read more »PTPRM
Kamis, 2025-11-20 07:23:37brain cells. PTPmu has been shown to increase the mRNA of the K+ channel Kv1.5 in cardiac myocytes when CHO cells expressing PTPmu are cultured with cardiac...
Click to read more »Corticotropin-releasing hormone receptor
Selasa, 2026-08-11 22:51:43neuronal excitability in the hippocampus by modulating potassium channels (KV1 subfamily), increasing population spike amplitudes through presynaptic mechanisms...
Click to read more »Gintonin
Jumat, 2025-11-07 11:35:19(2013). "Activation of lysophosphatidic acid receptor by gintonin inhibits Kv1.2 channel activity: Involvement of tyrosine kinase and receptor protein tyrosine...
Click to read more »Shaker (gene)
Rabu, 2025-03-26 18:32:21structure determination of AgTx2-MTX chimera, a new potential blocker for Kv1.2 channel, derived from MTX and AgTx2 scorpion toxins". Protein Science....
Click to read more »Discrepin
Selasa, 2026-06-09 22:50:11toxin BmTx3 to its receptor site, where other K+ channel blockers (Kv1-, Kv3.4-, Kv4.2/4.3 family blockers) were unable to compete with this toxin. These...
Click to read more »List of minor planets: 99001–100000
Senin, 2026-06-15 07:04:1510, 2002 Palomar NEAT · 3.2 km MPC · JPL 99787 2002 JM146 — May 15, 2002 Haleakala NEAT V 1.2 km MPC · JPL 99788 2002 KV1 — May 16, 2002 Socorro LINEAR...
Click to read more »KCNAB3
Rabu, 2024-07-17 05:39:27Isbrandt D, Pongs O (Feb 1999). "Coexpression of the KCNA3B gene product with Kv1.5 leads to a novel A-type potassium channel". J Biol Chem. 273 (52): 35095–101...
Click to read more »Antonello Bonci
Selasa, 2026-08-11 15:42:56TP; Bonci, A (2013). "Dynamic interaction between sigma-1 receptor and Kv1.2 shapes neuronal and behavioral responses to cocaine". Cell. 152 (1–2):...
Click to read more »Potassium channel tetramerisation domain
Minggu, 2023-12-03 23:24:38the basis of sequence similarity and function. Four of these subfamilies, Kv1 (Shaker), Kv2 (Shab), Kv3 (Shaw) and Kv4 (Shal), consist of pore-forming...
Click to read more »AsKC11
Jumat, 2026-05-15 12:34:42Kir2.1 or the voltage-gated potassium channels, Kv1.1-1.4 channels, and showed a small inhibition of Kv1.6. channels. AsKC11 binding is reversible. For...
Click to read more »KCND2
Sabtu, 2025-07-19 13:14:47DF, Fedida D (2002). "N-terminal PDZ-binding domain in Kv1 potassium channels". FEBS Lett. 531 (3): 529–537. doi:10.1016/S0014-5793(02)03572-X. PMID 12435606...
Click to read more »PTPRA
Kamis, 2025-11-20 06:58:13participates in the m1 muscarinic acetylcholine receptor-dependent regulation of Kv1.2 channel activity". EMBO J. 18 (1): 109–18. doi:10.1093/emboj/18.1.109....
Click to read more »Michael G. Hanna
Senin, 2026-05-18 13:50:51(1999). "A novel mutation in the human voltage-gated potassium channel gene (Kv1.1) associates with episodic ataxia type 1 and sometimes with partial epilepsy"...
Click to read more »GRIK2
Selasa, 2026-02-24 06:02:47pore loop structure is similar to that found in K+ channels (e.g. the human Kv1.1 channel, whose pre-mRNA is also subject to A to I RNA editing). The diversity...
Click to read more »List of minor planets: 732001–733000
Rabu, 2026-04-01 21:22:54Dictionary of Minor Planet Names. Springer Berlin Heidelberg. ISBN 978-3-540-00238-3. Retrieved 27 July 2016. Schmadel, Lutz D. (2006). Dictionary of Minor...
Click to read more »Guangxitoxin
Kamis, 2026-04-23 23:29:09Gaisano HY, Salapatek AM, Backx PH, Wheeler MB (August 2001). "Members of the Kv1 and Kv2 voltage-dependent K(+) channel families regulate insulin secretion"...
Click to read more »Index of ancient Egypt–related articles
Kamis, 2026-08-13 17:13:23Kulubnarti church Kulubnarti Kumma (Nubia) Kurna Kurt Sethe Kushite religion KV1 KV2 KV3 KV4 KV5 KV6 KV7 KV8 KV9 KV10 KV11 KV12 KV13 KV14 KV15 KV16 KV18 KV19...
Click to read more »1st Guards Cavalry Corps
Selasa, 2025-12-23 06:21:25traditional sabre of the Cossack horsemen. The cavalrymen, along with the T34 and KV1 tanks wielded by the 112th Tank Division battled ferociously against the...
Click to read more »List of minor planets: 697001–698000
Rabu, 2026-04-01 21:19:33Dictionary of Minor Planet Names. Springer Berlin Heidelberg. ISBN 978-3-540-00238-3. Retrieved 27 July 2016. Schmadel, Lutz D. (2006). Dictionary of Minor...
Click to read more »Alpha-actinin-2
Senin, 2026-04-27 12:04:56Fedida D (July 2003). "SAP97 increases Kv1.5 currents through an indirect N-terminal mechanism". FEBS Letters. 547 (1–3): 205–11. doi:10.1016/S0014-5793(03)00668-9...
Click to read more »List of minor planets: 426001–427000
Rabu, 2026-04-01 20:51:25Dictionary of Minor Planet Names. Springer Berlin Heidelberg. ISBN 978-3-540-00238-3. Retrieved 27 July 2016. Schmadel, Lutz D. (2006). Dictionary of Minor...
Click to read more »Unconventional myosin-Va
Sabtu, 2025-10-04 16:16:29MYO5B are involved with Kv1.5 (encoded by Potassium voltage-gated channel subfamily A member 5, KCNA5) in the myocytes. Kv1.5 is associated with the...
Click to read more »List of minor planets: 643001–644000
Rabu, 2026-04-01 21:14:39Dictionary of Minor Planet Names. Springer Berlin Heidelberg. ISBN 978-3-540-00238-3. Retrieved 27 July 2016. Schmadel, Lutz D. (2006). Dictionary of Minor...
Click to read more »KCNE1
Selasa, 2025-10-21 19:26:29co-expressed with the Kv1.1 α subunit in Chinese Hamster ovary (CHO) cells, KCNE1 traps the N-type (rapidly inactivating) Kv1.4 α subunit in the ER/Golgi...
Click to read more »List of minor planets: 458001–459000
Minggu, 2026-05-10 07:01:47Dictionary of Minor Planet Names. Springer Berlin Heidelberg. ISBN 978-3-540-00238-3. Retrieved 27 July 2016. Schmadel, Lutz D. (2006). Dictionary of Minor...
Click to read more »List of minor planets: 508001–509000
Rabu, 2026-04-01 20:59:34Dictionary of Minor Planet Names. Springer Berlin Heidelberg. ISBN 978-3-540-00238-3. Retrieved 27 July 2016. Schmadel, Lutz D. (2006). Dictionary of Minor...
Click to read more »AmmTX3
Selasa, 2026-06-02 14:48:10channels almost completely. A-type potassium currents can be generated by Kv1.4, Kv3.3, Kv3.4, all members of Kv4 and Erg3 channels. The influence of AmmTX3...
Click to read more »MLC1
Senin, 2026-08-10 09:46:42homology with the KCNA1 shaker-related voltage-gated potassium channel (Kv1.1). This analysis suggests that MLC1 may be a cation channel.[needs update]...
Click to read more »Gene therapy for epilepsy
Selasa, 2026-06-23 20:46:52tone, it is possible to restore balance between inhibition and excitation. Kv1.1 is a voltage-gated potassium channel encoded by the KCNA1 gene. It is widely...
Click to read more »List of minor planets: 328001–329000
Rabu, 2026-03-25 22:52:59JPL 328339 2008 KU1 — May 26, 2008 Kitt Peak Spacewatch · 1.3 km MPC · JPL 328340 2008 KV1 — May 26, 2008 Kitt Peak Spacewatch WIT 1.2 km MPC · JPL 328341...
Click to read more »KCNE5
Senin, 2025-09-29 21:14:47KCNQ2/3 or KCNQ5 channel activity, KCNE5 inhibits KCNQ4 in CHO cells but not in oocytes. Although it has no known effects on hERG (Kv11.1) or Kv1.x family...
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