KNOX signed on in 1949 with a full service format blending music, news, talk, and radio dramas. It later became a Top 40 station, and changed to a mainly news/talk format in the 1980s. The lineup of local on-air hosts has undergone several changes since then and has included names like Jim Bollman, Scott Hennen, and Jarrod Thomas.
News Talk 1310 KNOX's local news team consists of Doug Barrett and Pat Sweeney.
On January 11, 2012, KNOX began broadcasting on FM translator K300BG (107.9 FM) in Grand Forks. K300BG had been broadcasting KGFK (AM 1590), which moved to 95.7 FM as it has a stronger signal in Grand Forks. In May 2021, second FM translator K277DN (103.3 FM) in Grand Forks signed on for better rural coverage from the KZLT/KZGF transmitter tower, including coverage of Crookston, while K300BG continues to cover the immediate Grand Forks–East Grand Forks area. K277DN also has stronger coverage than K300BG in some parts of Grand Forks–East Grand Forks due to less adjacent channel interference from full-power KJKJ "KJ108" and co-channel interference from Fargo's KPFX "107.9 The Fox".