He was elected to the House of Commons in 1807, sitting as MP for Newton until 1818. He subsequently became involved in the politics of the town of Warrington, helping to establish the Warrington Operative Conservative Association.[2] Such associations were established in the north west of England in order to enlist the support of working class men against the emerging Radical and Chartist movements.[3]
He returned to parliament at the 1835 general election when he won the parliamentary borough of Warrington from the Liberal Party. He sat as the town's MP until he retired in 1847. He was a strong defender of the established church, and was opposed to the endowment of Roman Catholic priests and the appropriation of church property for secular purposes. He also supported the improvement of working conditions, in particular the Ten Hours Act of 1847.[4]
Blackburne married his cousin, Anne Bamford. Their son, also named John Ireland Blackburne, was also a member of parliament from 1875 – 1885.[5]