He was the second son of Roger Booth, of Mollington, Cheshire.[2] He succeeded to the Mollington estates on the death of his elder brother, Thomas Booth, in 1528, when he is described as being thirty-three years of age.[2] He was educated at Brasenose College, Oxford,[2] where he graduated with a BA in 1512 and a MA in 1516.[3] Booth was collated to the archdeaconry of Hereford on 29 January 1522 o.s. (1523 n.s.).[2][4] He died on 15 August 1542,[2][4] and his niece, Agnes Booth, daughter of his brother, Charles Booth, was found to be his heir then aged nine years.[2]