In 2004 he starred in and associate produced Bomb the System.[3]
Dedio's first screenplay titled Downtown: A Street Tale was completed in 2006.[4]
Dedio then co-produced the documentary The Providence Effect about the school Providence St. Mel, where President Obama was a community organizer[clarification needed] before becoming President of the United States. Dedio then starred opposite Academy Award winner Melissa Leo in the South African drama Lullaby directed by Academy Award nominee Darryl Roodt.
In 2013 Dedio produced the film Musical Chairs directed by Academy Award nominee Susan Seidelman. The film earned the producers a GLADD nomination for Best Feature.
Dedio then wrote and starred in the title role of the hit award-winning film Tio Papi. Dedio was nominated as Best Actor at the 2013 Imagen Awards for his portrayal of Ray Ray Dominguez as well as receiving a key to the city of Miami and Miami Beach for his work on the project. Dedio's next film was the cult classic 36 Saints.