Jessica Aguilar made her professional mixed martial arts debut on February 18, 2006 at Absolute Fighting Championships 15. She faced Lisa Ellis and was defeated by submission due to a rear-naked choke in the second round.
On February 17, 2007, Aguilar faced Japanese pro wrestler Sumie Sakai at Combat Fighting Championship 3. She defeated Sakai by unanimous decision.[5]
Aguilar faced Valerie Coolbaugh on March 5, 2010 at Action Fight League: Rock-N-Rumble 2. She defeated Coolbaugh by submission due to a triangle choke in the second round.[6]
Aguilar returned to Action Fight League on June 4, 2010 at Rock-N-Rumble 3. She defeated Catia Vitoria by TKO in the first round.[7]
On June 23, 2010, Bellator Fighting Championships announced that Aguilar had signed on to take part in the promotion's 115 lbs women's tournament.[8]
Aguilar made her Bellator debut at Bellator 24 on August 12, 2010. She defeated Lynn Alvarez by submission due to an arm-triangle choke in the first round to advance to the semi-finals of the Bellator tournament.[9]
On September 30, 2010, Aguilar faced Zoila Frausto Gurgel at Bellator 31. She was defeated by a controversial split decision, having dominated most of the match.[10]
On June 25, 2011, Aguilar returned to Bellator and faced Carla Esparza at Bellator 46. She defeated Esparza by split decision.[13]
Aguilar agreed to rematch Zoila Frausto Gurgel in a non-title bout at a Bellator event in late October.[14] However, she withdrew from the planned fight due to a prolonged recovery from foot surgery after her June win over Esparza.[15]
Aguilar faced Lisa Ellis in a rematch at Bellator 58 on November 19, 2011.[16] She missed weight for the fight, but won by unanimous decision.[17]
Aguilar next faced Patricia Vidonic at Fight Time Promotions 8 on February 17, 2012.[18] She defeated Vidonic by unanimous decision.[19]
Aguilar returned to Bellator to face Megumi Fujii at Bellator 69 on May 18, 2012.[20] She defeated Fujii by unanimous decision.[21]
On March 28, 2013, Aguilar faced Patricia Vidonic in a rematch at Bellator 94.[22] She won the back-and-forth fight via split decision.[23]
Along with Jessica Eye, Aguilar was released by Bellator on August 13, 2013. Aguilar and Eye were the last remaining female fighters on the Bellator roster.[24][25]
Aguilar faced Megumi Fujii in a rematch at Vale Tudo Japan 3rd on October 5, 2013 in Tokyo, Japan.[26] Aguilar initially won by TKO when the doctor stopped the fight after round two due to a Fujii eye injury that was caused by two accidental eye pokes.[27] The result of the fight was later changed to a technical majority decision win for Aguilar.[28]
World Series of Fighting
It was announced on November 11, 2013 that Aguilar had signed with World Series of Fighting, becoming the first female fighter to sign with the promotion.[29]
In her first title defense, Aguilar faced Emi Fujino on June 21, 2014 at WSOF 10.[32] She won the fight via unanimous decision.[33]
Aguilar made her second title defense against Kalindra Faria on November 15, 2014 at WSOF 15.[34] She again was victorious via unanimous decision.[35]
On May 18, 2015 Aguilar was granted her release from WSOF, to pursue fighting in the UFC.[36]
Ultimate Fighting Championship
On June 11, 2015, it was announced that Aguilar officially signed with the Ultimate Fighting Championship (UFC). She made her debut against Cláudia Gadelha on August 1, 2015 at UFC 190.[37] She lost the fight by unanimous decision.[38]
Aguilar's next bout was expected to be against Juliana Lima at UFC 197.[39] However, on March 18 she revealed that she had torn her ACL and that it would require surgery; she would subsequently be replaced by Carla Esparza.[40][41]
Aguilar next faced Cortney Casey at UFC 211 on May 13, 2017.[42] She lost the fight via unanimous decision. However, the result of the fight was overturned to a No Contest after an in-competition drug test by Casey tested positive for elevated levels of testosterone. In turn, on June 30, the TDLR lifted Casey's three-month suspension and gave back her victory, which was overturned to a no contest.[43]
Aguilar was scheduled to face Jodie Esquibel on June 1, 2018 at UFC Fight Night 131.[46] Aguilar successfully weighed in, but the bout was removed from the card the day of the event by the NYSAC due to a concern over a medical issue with Aguilar.[47] The pair eventually faced each other at UFC Fight Night 133 on July 14, 2018.[48] Aguilar won the fight by unanimous decision.[49]
On May 16, 2019 it was reported that Aguilar was released by UFC.[54]
Xtreme Fighting Championships
On October 5, 2020 it was announced that Aguilar signed with Xtreme Fighting Championships and would make her debut in November 2020.[55] Later, it was announced that Aguilar would make her promotional debut against Danielle Taylor at XFC 43 on November 11, 2020.[56] She lost the fight via split decision.[57]
Outside of mixed martial arts, Aguilar currently manages franchise development for the Boca Tanning Club chain in Florida.[59] She is openly lesbian and is dating actress Shalita Grant as of 2020.[60][61][62]