Cotton contributed unique and challenging slide guitar to live performances, Strictly Personal, Mirror Man and Trout Mask Replica; for which he was renamed Antennae Jimmy Semens. He left the Magic Band in 1970 after being attacked by temporary drummer Jeff Burchell during a group "talk" and having ribs broken, and having experienced the reclusive 8 months of rehearsals for Trout Mask Replica during which Beefheart experimented on the group members with sleep deprivation, food deprivation, and physical violence in an attempt to break their mental state down.
He renewed his professional relationship with Merrell Fankhauser (of The Exiles) in a band called MU.[2] Despite a critically acclaimed album there was no commercial success, and he retired from the music business in 1975 to study the Christian Ministry. In 1981, long after the group had disbanded, a second LP of unreleased MU[3] material was issued.
In 2022 a 50 year recording hiatus ended with his first solo album, The Fantasy of Reality.[4]