Wynne studied at Harvard University, receiving a bachelor's degree in 1964, master's degree in 1965 and doctorate in 1969 in applied physics. He then joined IBM Research, first at IBM Zurich Research Laboratory and then at the Thomas J. Watson Research Center.
His research has been in nonlinear optics of semiconductors and insulators, nonlinear spectroscopy of atomic and molecular vapors physics of Clusters, using the laser to etch and in medicine (e.g., fluorescence studies of tissue).
In 1981, with Rangaswamy Srinivasan and Samuel E. Blum at IBM, he pioneered the use of excimer lasers in surgery. Based on an early experiment in which an excimer laser was able to make clean cuts in dead cartilage from a Thanksgiving turkey, without thermal damage,[3] they recognized the potential for surgery. Srinivasan later developed on this basis, with Bodil Braren and Stephen Trokel, applications to eye surgery in the form of photorefractive keratectomy (PRK) and LASIK. Wynne himself worked on applications in dermatology with doctors at New York University Medical School (1985).[4][5]
Wynne was Manager for nonlinear spectroscopy, laser physics and chemistry and biology and molecular physics at the IBM Thomas J. Watson Research Center. He was a visiting scholar at the University of Chicago, the University of Rochester, the Dartmouth College and Johns Hopkins University. He is now responsible for education outreach at the IBM Thomas J. Watson Center. He also conducts research on the development of ″smart scalpels″ with excimer lasers for the removal of necrotic skin from burn injuries.[6]
