James Hume may refer to:

• James Hume (architect) (1798–1868), architect in Sydney, Australia
• James Hume (cricketer) (1858–1909), Scottish-born New Zealand cricketer
• James Hume (magistrate) (1808–1862), British magistrate and political commentator in Calcutta
• James Hume (mathematician) (fl. 1639), Scottish mathematician given credit for introducing the modern exponential notation
• James Hume (superintendent) (1823–1896), New Zealand asylum superintendent
• James Hume (rugby union) (born 1998), Irish rugby union player
• James B. Hume (1827–1904), lawman in the American West
• James Deacon Hume (1774–1842), English official, economic writer and advocate of free trade
• Jim Hume (born 1962), Scottish Liberal Democrat politician

• All pages with titles containing James Hume
• James Humes (disambiguation)

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