JKAMP

JKAMP

Identifiers

JKAMP, C14orf100, HSPC213, HSPC327, JAMP, CDA06, JNK1/MAPK8-associated membrane protein, C24orf100, JNK1/MAPK8 associated membrane protein

External IDs

OMIM: 611176; MGI: 1915057; GeneCards: JKAMP

Gene location (Human)

Chr.	Chromosome 14 (human)^[1]

Band	14q23.1	Start	59,484,443 bp^[1]
Band	14q23.1	End	59,505,410 bp^[1]

Gene location (Mouse)

Chr.	Chromosome 12 (mouse)^[2]

Band	12\|12 C3	Start	72,132,363 bp^[2]
Band	12\|12 C3	End	72,148,235 bp^[2]

RNA expression pattern

Human

Mouse (ortholog)

Top expressed in

islet of Langerhans

tibia

monocyte

retinal pigment epithelium

pancreatic epithelial cell

parietal pleura

cardiac muscle tissue of right atrium

skin of arm

bronchial epithelial cell

rectum

Top expressed in

facial motor nucleus

Rostral migratory stream

retinal pigment epithelium

ciliary body

Epithelium of choroid plexus

iris

anterior horn of spinal cord

substantia nigra

external carotid artery

internal carotid artery

More reference expression data

n/a

Gene ontology
Molecular function	ubiquitin protein ligase binding
Cellular component	integral component of membrane endoplasmic reticulum membrane endoplasmic reticulum membrane
Biological process	response to unfolded protein ubiquitin-dependent ERAD pathway
Sources:Amigo / QuickGO

Databases

NCBI: entry; OMA: entry

Species

Human

Mouse


51528


104771


ENSG00000050130


ENSMUSG00000005078


Q9P055


Q8BI36

RefSeq (mRNA)

NM_001098625 NM_001284201 NM_001284202 NM_001284203 NM_001284204
NM_016475


NM_001205067 NM_024205

RefSeq (protein)

NP_001092095 NP_001271130 NP_001271131 NP_001271132 NP_001271133
NP_057559 NP_001271130.1


NP_001191996 NP_077167

Location (UCSC)

Chr 14: 59.48 – 59.51 Mb

Chr 12: 72.13 – 72.15 Mb

PubMed search

^[3]

^[4]

View/Edit Human

View/Edit Mouse

JNK1-associated membrane protein is a protein that in humans is encoded by the JKAMP gene.^[5]^[6]^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000050130 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000005078 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Kadoya T, Khurana A, Tcherpakov M, Bromberg KD, Didier C, Broday L, Asahara T, Bhoumik A, Ronai Z (Sep 2005). "JAMP, a Jun N-terminal kinase 1 (JNK1)-associated membrane protein, regulates duration of JNK activity". Mol Cell Biol. 25 (19): 8619–30. doi:10.1128/MCB.25.19.8619-8630.2005. PMC 1265750. PMID 16166642.
^ Tcherpakov M, Delaunay A, Toth J, Kadoya T, Petroski MD, Ronai ZA (Apr 2009). "Regulation of endoplasmic reticulum-associated degradation by RNF5-dependent ubiquitination of JNK-associated membrane protein (JAMP)". J Biol Chem. 284 (18): 12099–109. doi:10.1074/jbc.M808222200. PMC 2673279. PMID 19269966.
^ "Entrez Gene: C14orf100 chromosome 14 open reading frame 100".

Further reading

Zhang QH, Ye M, Wu XY, et al. (2001). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934. PMID 11042152.
Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Behrends U, Schneider I, Rössler S, et al. (2003). "Novel tumor antigens identified by autologous antibody screening of childhood medulloblastoma cDNA libraries". Int. J. Cancer. 106 (2): 244–51. doi:10.1002/ijc.11208. PMID 12800201.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.

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