Ixodes marxi is a species of tick, commonly known as the squirrel tick.[1] It is a known vector of Powassan virus and can transmit the virus to human beings. [2] These ticks can be found in numerous states of the United States as well as numerous Canadian provinces. Nymphs have been found on vegetation. Hosts include the eastern chipmunk,[3]American red squirrel, Eastern gray squirrel, flying squirrels, snowshoe hares, foxes, and raccoons.[4]