Z. lineatus is endemic to southern Italy and Sicily. The northern limit of its geographical range is the Province of Caserta in the west and the Province of Foggia in the east. It is absent from the Salentine Peninsula (Salento), which is the "heel" of the "boot" of Italy.
The Italian Aesculapian snake is a medium to large snake that reaches a maximum total length (including tail) of 2 m (6+1⁄2 ft). Dorsally, it is yellowish brown and may have four dark brown stripes. If present, the stripes are of equal width and equidistant. The dorsal scales are smooth. The iris of the eye is red, giving it the common name in Italian of saettone occhirossi (red-eyed racer).
Camerano L (1891). "Monografia degli ofidi italiani. Parte seconda — colubridi e monografia dei cheloni italiani ". Memorie della Reale Accademia delle Scienze di Torino, Serie seconda41 (2): 403–469. (Callopeltis longissimus Var. lineata, p. 458). (in Italian).
Lenk P, Wüster W (1999). "A Multivariate Approach to the Systematics of Italian Rat Snakes of the Elaphe longissima Complex (Reptilia, Colubridae): Revalidation of Camerano's Callopeltis longissimus var. lineata". The Herpetological Journal9 (4): 153–162.
Utiger U, Helfenberger N, Schätti B, Schmidt C, Ruf M, Ziswiler V (2002). "Molecular systematics and phylogeny of Old World and New World ratsnakes, Elaphe Auct., and related genera (Reptilia, Squamata, Colubridae)". Russian Journal of Herpetology9 (2): 105–124.