On 22 February 1608, she married Alfonso, Hereditary Prince of Modena (son of Cesare d'Este and Virginia de' Medici) in Turin.[2] This was a happy marriage; Alfonso was loving and loyal towards his wife. Within two years, Isabella bore Alfonso a son, Francesco who would one day succeed his father as Duke of Modena and Reggio.
When Isabella died in childbirth on 28 August 1626, Alfonso was heartbroken; he never remarried and died in 1644. Isabella had been constantly pregnant during much of her 18 years of marriage, giving birth almost once per year. She had died before her husband became duke, so she was never Duchess of Modena.
Condren, John (2024). Louis XIV and the Peace of Europe: French Diplomacy in Northern Italy, 1659–1701. Taylor & Francis.
Hester, Nathalie (2017). "Baroque Italian Epic from Granada to the New World: Columbus Conquers the Moors". In Horodowich, Elizabeth; Markey, Lia (eds.). The New World in early modern Italy, 1492-1750. Cambridge, United Kingdom: Cambridge University Press. pp. 270–287. ISBN978-1-107-12287-1. OCLC987794999.
Osbourne, Toby (2002). Dynasty and Diplomacy in the Court of Savoy: Political Culture and the Thirty Years' War. Cambridge University Press.
