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He studied at the history department of the Leningrad State University under professors such as Vasily Struve and Alexander Tyumenev.
Amusin was twice (in 1928 and 1938) arrested and sentenced for Zionist connections and "anti-Soviet" activity (acquitted posthumously in 1989). Graduated from the Historical Faculty of Leningrad University (1935–1941). Served as a medical officer during the Second World War.