This article needs additional citations for verification. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed. Find sources: "I Can't Turn You Loose" – news · newspapers · books · scholar · JSTOR (July 2016) (Learn how and when to remove this message)

"I Can't Turn You Loose" is a song written and first recorded by American soul singer Otis Redding. It was released as the B-side to his 1965 single "Just One More Day". The up-tempo song became a bigger hit on the US R&B chart than its A-side and was one of Redding's signature songs and often appeared in his live performances.

Parts of the melody were used by the Blues Brothers to both open and close their shows, including their performances in the Blues Brothers movie and their performance on Saturday Night Live.

• In 1968, the Chambers Brothers' version of this song reached number 37 on the Billboard Hot 100 singles chart.^[2] In Canada it reached number 29.^[3]

• The Blues Brothers Band performed the song in full in the performance for its 1990 live album The Blues Brothers Band Live in Montreux, which was included in the album.