Healthy in 2009, Noesí pitched well for Charleston and the High–A Tampa Yankees.[3] He was named Pitcher of the Week for the week of 18 May and was a South Atlantic League Mid-Season All-Star.[4] Following the 2009 season, Noesí was added to the 40-man roster to protect him from the Rule 5 draft.[5]
On 13 April 2011, Noesí was called up to the major leagues for the first time in his career, replacing relief pitcher Luis Ayala, who the Yankees put on the disabled list.[9] He was optioned to Triple–A on 22 April without having made his major league debut, briefly becoming a phantom ballplayer[10]
Noesí made his major league debut on 18 May 2011, pitching four scoreless innings of relief and earning the win in an extra-innings game against the Baltimore Orioles. He made his first MLB start on 21 September.[11]
Seattle Mariners
On 23 January 2012, the Yankees traded Noesí to the Seattle Mariners along with Jesús Montero in exchange for Michael Pineda and minor league pitcher José Campos.[12][13] Noesí performed poorly in the first half of the 2012 season, going 2–11 with a 5.77 ERA. He was demoted to the Triple–A Tacoma Rainiers on 4 July.[14] Noesí was recalled on 4 September when rosters expanded.[15]
Noesí spent most of 2013 season shuttling back and forth between Seattle and Tacoma.[16] On 4 April 2014, Noesi was designated for assignment by the Mariners.[17]
Texas Rangers
On 12 April 2014, Noesi was traded to the Texas Rangers.[18] He made his Rangers debut against the Mariners two days later. He was designated for assignment on 22 April.[19]
Chicago White Sox
On 25 April 2014, Noesi was claimed off waivers by the Chicago White Sox.[20] In 28 games (27 starts) for the White Sox, he compiled an 8–11 record and 4.39 ERA with 117 strikeouts across 166 innings.
Noesí made 10 appearances for Chicago in 2015, struggling to an 0–4 record and 6.89 ERA with 22 strikeouts over 32+2⁄3 innings pitched. He was designated for assignment by the White Sox on 18 June 2015.[21] Noesí cleared waivers and was sent outright to the Triple–A Charlotte Knights on 26 June.[22]
Kia Tigers
Noesí signed a $1.7 million deal to pitch for the Kia Tigers of the KBO League in 2017. He became the second highest paid player in the KBO.[23] Noesí pitched to a 20–5 win–loss record with a 3.48 earned run average during the regular season and started Game 1 of the 2017 Korean Series.[24] On 1 December 2017, Noesí signed a one-year, $2 million contract with the Tigers.[25] On 4 December 2018, the Tigers announced that Noesí would not return with the team due to the recent increased tax rate on foreign players.[26]
Miami Marlins
On 17 January 2019, Noesí signed a minor league contract with the Miami Marlins.[27][28] On 6 August, the Marlins selected Noesí's contract.[29] On 16 October, Noesí was removed from the 40–man roster and sent outright to the Triple–A New Orleans Baby Cakes, and elected free agency the next day.[30][31]
Pittsburgh Pirates
On 17 December 2019, Noesí signed a minor league contract with the Pittsburgh Pirates.[32] On 8 July 2020, Noesí announced he would be opting out of the 2020 season during the COVID-19 pandemic.[33] He became a free agent on 2 November.[34]
Fubon Guardians
On 24 December 2020, Noesí signed a $500,000 contract with the Fubon Guardians of the Chinese Professional Baseball League for the 2021 season.[35][36] However, his contract was later terminated prior to the season on 21 February 2021 after he sustained an injury while training in the offseason.[37]
