The teeth of Hoplocetus are massive (95–150 mm in length; 27–47 in maximum diameter), robust and have a short enamel cap on the crowns.[3] They are somewhat larger than those of modern orcas[4] but considerably smaller than those of macroraptorial sperm whales, such as Zygophyseter, as well as those of Scaldicetus caretti.[5] They display a large degree of abrasion, suggesting a highly predatory niche comparable to that of modern orcas.[3] The genus of the latter, Orcinus, first appears in the middle Pliocene and it may have eventually replaced Hoplocetus.[3]
These teeth features also characterize the other extinct toothed whale genera, Diaphorocetus, Idiorophus and Scaldicetus, sometimes placed with Hoplocetus in the subfamilyHoplocetinae.[6] However, some of these taxa are fragmentary and have been used as wastebasket taxa for non-diagnostic material of stem physeteroids.