His Best Friend may refer to:

• His Best Friend (1918 film), a German silent film directed by Uwe Jens Krafft
• His Best Friend (1929 film), a German silent film directed by Harry Piel
• His Best Friend (1937 film), a German film remake, also directed by Piel
• His Best Friend (1962 film), a West German film directed by Luis Trenker

This disambiguation page lists articles associated with the title His Best Friend.
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