The High Street Historic District encompasses one hundred and twenty-four contributing buildings and one contributing structure in an upper- and middle-level residential section of Pottstown. This district includes late-19th and early-20th century mansions and stylish homes that were built between 1860 and 1941.[2]
Notable non-residential buildings include a gas station, which was erected sometime around 1928, St. John's Reformed Church, which was built in 1916, St. James Evangelical Lutheran Church, which was also built sometime around 1916, and the Pottstown Memorial Hospital, which was erected circa 1938.[2]
This district also includes the separately listed Grubb Mansion.[2]