Born in Paris, Le Tellier started his career as a scientific journalist, and joined Oulipo in 1992. As an author, he came to general attention in 1998 with the publication in France of his book Les amnésiques n'ont rien vécu d'inoubliable, a collection of one thousand very short sentences all beginning with "Je pense que" (I think that), published in English as A Thousand Pearls (for a Thousand Pennies). His rather complex novel Le voleur de nostalgie is a tribute to the Italian writer Italo Calvino. He is also one of the participants of Papous dans la tête, the cult literary quiz of France Culture, the French cultural radio station.
He became in 2002 a daily contributor to the website of the newspaper Le Monde with a short satirical chronicle called Papier de verre ("sandpaper").
He founded, with Frederic Pages and others, the "Association of Friends of Jean-Baptiste Botul" to promote this fictitious philosopher and his school of "Botulism".
One of his most recent publications is Esthétique de l’Oulipo (The Aesthetics of Oulipo), a very personal essay on literature under constraint, considered from a linguistic perspective.
Seven of his books have been translated into English, from Enough about love (Other Press) to The Sextine Chapel (Dalkey Archive).
Award
2020: Prix Goncourt for The Anomaly (French: L'anomalie). He is the first member of Oulipo to win the Goncourt.