Grape Island may refer to

• Grape Island (West Virginia), in the Ohio River
• Grape Island, West Virginia, an unincorporated community in Pleasants County, West Virginia
• Grape Island (Lake Michigan), part of the Beaver Island (Lake Michigan) archipelago
• Grape Island (Massachusetts), one of the Boston Harbor Islands
• Grape Island (Essex County, Massachusetts), Plum Island Sound, Ipswich, Massachusetts
• Grape Island (Lake Simcoe), Ontario, Canada

This disambiguation page lists articles associated with the title Grape Island.
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