The hotel began as the Saxony Hall, built in 1701 by Burgomaster Deiml.
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A later mayor, Becher, built a Lusthaus on a plot of land he owned at right-angles to the Saxony Hall. This became known as the Bohemia Hall. Jan Jiří Pop (German: Johann Georg Pupp), a confectioner, came to Karlovy Vary (that time known under its German name Karlsbad) in 1760 and worked for a local confectioner called Mitterbach. The widow of former mayor Becher sold a one-third share in the Bohemia Hall to Mitterbach's daughter, who married Pop in 1775. The following year, she bought another third and her husband the remaining third, giving the Pop/Pupp family complete ownership of the hall. At that time, Jan Jiří Pop started to use the German variant of his name.
The family prospered in the following decades and was able to buy the Saxony Hall in 1890. Between 1896 and 1907, the Viennese architects Fellner & Helmer rebuilt the various family-owned buildings into the neo-BaroqueGrandhotel Pupp that stands today. Up until the World War II the family continued to acquire neighbouring properties and incorporate them into the hotel complex.
After the war, the Edvard Beneš government of Czechoslovakia nationalized the hotel and it was renamed Grandhotel Moskva in 1950. The hotel's owners, along with almost the totality of the Karlovy Vary's population, were expelled. The hotel's original name was restored in 1989 and it has since been privatized.
