Gmina Sierpc is a rural gmina (administrative district) in Sierpc County, Masovian Voivodeship, in east-central Poland. Its seat is the town of Sierpc, although the town is not part of the territory of the gmina.
The gmina covers an area of 150.23 square kilometres (58.0 sq mi), and as of 2006 its total population is 7,141.