Gmina Hyżne is a rural gmina (administrative district) in Rzeszów County, Subcarpathian Voivodeship, in south-eastern Poland. Its seat is the village of Hyżne, which lies approximately 17 kilometres (11 mi) south-east of the regional capital Rzeszów.
The gmina covers an area of 50.98 square kilometres (19.7 sq mi), and as of 2006 its total population is 6,811.