He was the younger son of George Grahame Laird of Inchbraikie and his wife, Marion ("Mary") Rollo, daughter of Rollo of Duncrub. He was a great-grandson of William Graham, 1st Earl of Montrose.
Originally (from 1589) minister of Clunie he translated to Auchtergaven in 1595 and further translated to Scone in 1601,[1] and then in February 1603, he received crown provision to the bishopric of Dunblane, vacant by the resignation of Andrew Graham. George had to wait a few years to obtain consecration, but was consecrated at some date between 21 October 1610 and 3 May 1611.
On 26 August 1615, he was translated to the bishopric of Orkney. He held that bishopric for more than three decades. Graeme, along with all other bishops of Scotland, was deprived of his see on 18 November 1638. He renounced his rights to the bishopric a few months later, on 11 February 1639, after being threatened by the Assembly at Glasgow. By this action, he avoided excommunication, and retained his estate at Gorthie. He died on 19 December 1643.[1]
Keith, Robert, An Historical Catalogue of the Scottish Bishops: Down to the Year 1688, (London, 1924), pp. 181, 227
Watt, D. E. R.; Murray, A. L., eds. (2003), Fasti Ecclesiae Scotinanae Medii Aevi ad annum 1638, The Scottish Record Society, New Series, Volume 25 (Revised ed.), Edinburgh: The Scottish Record Society, ISBN0-902054-19-8, ISSN0143-9448