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Game Changer or Game Changers may refer to:

• Game Changer (Johnny Gill album), 2014, or the title song
• Game Changer (Rawsrvnt album), 2015
• Game Changer, an album by Ali Ryerson and the Jazz Flute Big Band
• Game Changer, an album by Golden Child
• "Game Changer", a song by James Reid from James Reid
• "Game Changer", a song by Imelda May from Life Love Flesh Blood
• "Game Changer", a song by Mist from Diamond in the Dirt
• "The Game Changer", a song by American rapper Saigon from The Greatest Story Never Told Chapter 2: Bread and Circuses

• "Game Changer" (Modern Family), an episode of Modern Family
• The Gamechangers, a 2015 BBC-produced docudrama about Rockstar Games and Jack Thompson
• Gareth Thomas: Game Changer - 2014, a documentary production of Zipline Creative Limited
• Survivor: Game Changers, the 34th season of U.S. reality series Survivor
• The Game Changer, a 2017 Chinese action film
• The Game Changers, a 2018 documentary directed by Louie Psihoyos
• Game Changer (game show), a comedy game show on the streaming service Dropout
• Game Changer (film), an Indian Telugu-language political action thriller film

• GameChanger, a mobile app and website that provides scorekeeping, stats, Live GameStreams
• GameChangers, an IT education and research program
• Game Changer, a proposal of Australia's The Wilderness Society
• Game Changer, a 2019 chess book by Matthew Sadler and Natasha Regan
• Game Changer, a 2021 young-adult fiction book by Neal Shusterman
• Game Changer, alternative title of a painting by Banksy, Painting for Saints

• Game Change (film), a 2012 American HBO political drama film
• Game Change (book), a book by John Heilemann and Mark Halperin about the 2008 United States presidential election
• Double Down: Game Change 2012, a book by John Heilemann and Mark Halperin about the 2012 United States presidential election
• Changing the Game (disambiguation)
• Games for Change, a movement dedicated to using digital games for social change

This disambiguation page lists articles associated with the title Game Changer.
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