Neidhardt's independent research career began when he joined the Purdue faculty in 1961. He remained there until 1970, when he moved to the University of Michigan to become the chair of the microbiology department; he continued as chair for the following 13 years.[2] During that time he served in a number of other administrative roles, including associate dean for faculty in the medical school and Vice President for Research.[3][2][4] He became the Frederick G. Novy Distinguished University Professor of Microbiology and Immunology in 1989 and retired, assuming professor emeritus status, in 1999.[2]
Neidhardt authored or coauthored several widely recognized textbooks and reference works, including an important treatise on bacterial growth titled Escherichia coli and Salmonella: Cellular and Molecular Biology.[2] He spent almost twenty years on the board of the Waksman Foundation for Microbiology housed at Swarthmore College and served as its president.[5] He served as the president of the American Society for Microbiology in 1982.[2][6]
Neidhardt was a Quaker and was noted by friends for his dedication to social causes, including support for women and minority scientists.[1] Neidhardt had three children. He died on October 7, 2016, in Tucson, Arizona, of injuries stemming from a fall.[3]
^[F. G. Novy Distinguished University Professor "Frederick C. Neidhardt, Ph.D."] University of Michigan. Retrieved 12 January 2017. {{cite web}}: Check |url= value (help)