Frank Harris Quillen (December 18, 1920 – September 21, 1990) was an American football end.

Quillen was born in Ridley Park, Pennsylvania, and attended Ridley Park High School and the Franklin & Marshall Academy. He played college football for Penn.^[1]

He played professional football in the All-America Football Conference for the Chicago Rockets from 1946 to 1947. He appeared in 20 games, six as a starter, and caught 20 passes for 256 yards and three touchdowns.^[1]

After retiring from football, Quillen worked for 40 years with Chester Mack Sales & Services in Delaware. He died in Hockessin, Delaware, in 1990.^[2]