In 1958, Salvatore became the chairman of L&M Beverage Co. Inc., a wholesale beer distributor and operated the business until he sold it in 2001.[4]
He was elected to the Pennsylvania House of Representatives for the 170th district and served for five consecutive terms. He was elected Minority Caucus Administrator from 1977 to 1978 and again from 1983 to 1984. He was elected Majority Caucus Administrator from 1979 to 1982. He was not a candidate for reelection to the House in 1984.
He was elected to the Pennsylvania State Senate for the 5th district and served from 1985 to 2000. He was an outspoken critic of Mayor Wilson Goode. He presented the legislature with a bill proposing secession of Northeast Philadelphia from the rest of the city to form an entity called Liberty County but it found no broad political support.[5] He lost reelection to the Senate in 2000.[2]
He died in July 2014 at a Holy Redeemer Hospital in Meadowbrook, Pennsylvania[6][4] and is interred at the Resurrection Cemetery in Philadelphia.[2]