The Evandro Chagas Institute (Portuguese Instituto Evandro Chagas, or IEC) is a non-profit organization which promotes public health in Brazil named after Evandro Chagas.^{[citation needed]}

In the 1940s fisherman Henrique Penna from the Rockefeller Foundation in Rio de Janeiro reported that he had discovered cases of leishmaniasis in Brazil's countryside.^[1] The disease had not been previously detected in Brazil, and as a response, Carlos Chagas of the Oswaldo Cruz Institute organized a commission leishmaniasis to be headed by his son Evandro Chagas.^{[citation needed]}

In 1938 this commission became the Instituto de Pathologia Experimental do Norte, or Northern Institution for Experimental Pathology (IPEN), with a mission to study leishmaniasis and other regional diseases. In 1940 Evandro Chagas died in a plane crash. To acknowledge his work as a scientist, the government changed the name of the former IPEN into the Evandro Chagas Institute.^[2]

The IEC organized local volunteers to participate in the iPrEx study, which was a clinical trial testing the efficacy of a drug used as a pre-exposure prophylaxis against HIV infection.^{[citation needed]}

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