In the 2007 Rule 5 draft, Meek was selected from the Devil Rays by the Pittsburgh Pirates. This required that Meek remain on the active roster of the Pirates for the entire 2008 season or else the Pirates would have to offer him back to the Devil Rays for half the amount they paid to acquire him.[3]
Meek made his major league debut on April 2, 2008 with the Pittsburgh Pirates. He would record his first career loss in extra innings against the Chicago Cubs on April 7, 2008. Meek made nine relief appearances, going 0–1 with a 6.92 ERA, before being designated for assignment on May 4, 2008. He was offered back per Rule 5 guidelines on May 14. The Pirates paid cash to keep him and sent him down to their minor league teams. After pitching 9 games with the Double-A Altoona Curve, Meek was promoted to the Triple-A Indianapolis Indians.
Meek spent the 2009 season in the bullpen with the Pirates. He finished the season with a 1–1 record in 41 appearances, had a 3.45 ERA, gave up 2 home runs, 0 hit batsmen, 29 walks, 42 strikeouts, a .209 average against, and a 1.34 WHIP, in 47.0 innings pitched.
The 2010 season was Meek's first full season in the Majors. He was often asked by manager John Russell to pitch multiple innings in relief. Meek's performance rivaled other excellent closers like Joakim Soria and Brian Wilson despite not being one himself.[4] Early in the season when Dotel had given up runs in six straight games as the closer, Meek had an opportunity in the role and earned his first Major League save on April 29, 2010 to close out a 2–0 win over the Los Angeles Dodgers.[5] On May 14, 2010 against the Chicago Cubs at Wrigley Field, Meek entered the game in the 6th inning with the score tied 6–6, and he pitched two scoreless innings of relief, striking out four of the seven Cubs hitters he faced including Derrek Lee, Xavier Nady and Alfonso Soriano in the bottom of the 7th. The Pirates rallied behind his strong pitching to win the game 10–6.[6]
Meek delivered one of his finest performances of the season against the Washington Nationals on June 10, 2010, coming in to relieve Pirates starter Zach Duke with the bases loaded and no outs. He quickly forced Willie Harris to line into a double play before retiring Cristian Guzmán, needing only six pitches to get out of the inning with no runs in.[7] Due to his excellent work, he was named to the 2010 MLB All Star Game. At the time of his selection on July 4, 2010, Meek carried a 4–2 record with a 0.96 ERA, a mark that lead all National League relievers. "It's surprising", Meek said. "A lot of starters and closers go to the game. I've always said there are a lot of great middle relievers out there who deserve to go to the game. I think they're overlooked a little bit. It's amazing to be selected, an overwhelming feeling."[8] Meek was the first Pirate reliever selected who was not a closer since Mace Brown in 1938 – before the closer position emerged. The Pirates celebrated his nomination at PNC Park with an 8–5 victory over the visiting Philadelphia Phillies, a game where Meek was the winning pitcher.[9]
On August 3, 2010, Meek recorded his first career base hit, off fellow reliever Jordan Smith of the Cincinnati Reds. Meek finished the 2010 season with a 2.14 ERA, 70 strikeouts, 4 saves, 15 holds, and a 5–4 record, all career-highs.
After several injuries in 2011, Meek saw a decrease in fastball velocity.[10]
Meek started the 2012 season with Pittsburgh, but on May 1, Meek was optioned to Triple-A Indianapolis. Meek was 0-0 with a 5.59 ERA in 9 games with a .293 opposing batting average. He was recalled to the Pirates on July 21, 2012, after an injury to reliever Juan Cruz. But was sent back down on July 26, to make room for highly anticipated prospect Starling Marté. Meek was designated for assignment by the Pirates on September 10, 2012.[11] In October 2012, Meek elected minor league free agency.[12]
Texas Rangers
On December 6, 2012, Meek signed a minor league contract with the Texas Rangers the deal included an invitation to spring training. He elected free agency after the season on November 4.
Baltimore Orioles
On February 5, 2014, Meek signed a minor league contract with the Baltimore Orioles.[13] After a strong spring training, he made the Opening Day roster. On May 2, he was optioned to the Triple-A Norfolk Tides. He was recalled on May 15, and then designated for assignment on May 16.[14] Instead, the next day Meek was optioned back to Norfolk. On May 28, he was sent outright to Triple-A Norfolk Tides.[15] He had his contract selected to the major leagues again on June 6. On September 25,, Meek gave up a walk-off single to New York Yankees future hall-of-famer Derek Jeter in Jeter's final game at Yankee Stadium.[16] Subsequently, it was also Meek's last game in MLB. He was again sent outright to Triple-A Norfolk Tides on October 29. He elected free agency after the season on November 3.
Washington Nationals
On January 21, 2015, Meek signed a minor league contract with the Washington Nationals.[17] He was released on July 20.
Kia Tigers
On July 20, 2015, the Kia Tigers of the Korea Baseball Organization announced that they had signed Meek to a one-year deal worth $150,000. Meek filled a roster vacancy created by the club's release of former MLB pitcher Philip Humber on the same day.[18] He became a free agent following the season.
Meek's four-seam fastball normally sits around 95 mph, although he is capable of reaching 97–98 mph on occasion. It is his primary pitch, throwing it slightly over half the time. Despite missing the final two months of the 2009 Major League Baseball season, he added 8 pounds of muscle during the off-season and promised that he would be able to hit 100 mph in 2010.[19] Since his command has improved throughout his career – 5.55 walks per 9 innings in 2009 to around 2.10 in 2010 – opposing batters have shown more willingness to chase the pitch, even out of the strike zone to due his ability throw his other pitches for strikes.
However, after several injuries in 2011, Meek saw his fastball velocity decrease into the low to mid 90s, ranging from 90-95 mph.[10]
Meek's curveball is his primary off-speed pitch, with the velocity sitting around 79–82 mph.
Meek throws a cutter that was rated in August 2009 as the 3rd most effective cutter in Major League Baseball because of its runs above the MLB average.[20] The pitch has "unfair biting" movement, even against left-handed batters, according to Dejan Kovacevic of the Pittsburgh Post-Gazette. Average velocity is 92–93 mph and he normally likes to use it when he gets ahead in a count as a strikeout pitch. It is normally a very difficult pitch to hit well, helping him limit the number of extra base hits he allows.
Meek also throws a fourth pitch, an off-speed slider that is seldom used in pressure situations. The pitch normally sits around 80–82 mph, mainly incorporated to keep hitters out of a rhythm. His ability to throw four pitches well however, makes him rare as a relief pitcher as the normal reliever only possesses a three-pitch arsenal.[21]