The constituency Esch-sur-Alzette elected members to Luxembourg's national legislature, the Chamber of Deputies, from 1848 until its abolition in 1919. It was coterminous with the canton of Esch-sur-Alzette, in the south of the country.
After its abolition, it was replaced by Sud, which also included the canton of Capellen.
Members elected to represent Esch-sur-Alzette include Dominique Brasseur (1866–90), Xavier Brasseur (1902–12), and Léon Metz (1875–1918).