Epigonus is the Latinized form of epigonos (Greek: ἐπίγονος, "progeny"). It can refer to:

• Epigonos, pseudonym of Karl Adolph Gjellerup
• Epigonos of Telmessos, second son of Ptolemy I Epigone
• Antipater Epigonos, son of Epigonos of Telmessus
• Ptolemy Epigonos, co-regent of Egypt with Ptolemy II
• Epigonus, sculptor of the Pergamene school
• Epigonus of Ambracia, 6th century BC Greek musician
  • Epigonion, a musical instrument invented by Epigonus of Ambracia
• Epigonus of Thessalonica, author of two epigrams in the Greek Anthology

• Epigoni Sons of the failed Seven against Thebes.

• Vexillum epigonus, species of small sea snail
• Epigonus (fish), genus of cardinalfishes

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