Susana Trejos, a responsible doctor devoted to her patients, is about to marry Andrés del Valle, a lawyer with a shady past who carries on a secret affair with Ivonne, a hypocrite who claims to be Susana's best friend. However, Andrés' sister Paloma is the only one aware of the betrayal by both Andrés and his lover, but no one believes her. Susana is in love with Andrés, but he only wants to marry her to kill her and inherit her fortune. Mere hours before her church wedding, Susana receives a message that Andrés is in the Lacandon Jungle, gravely ill and near death.
True to her nature, Susana decides to fly by helicopter to save her beloved, only to find an archaeologist with the same name as her fiancé. Meanwhile, lawyer Andrés sets Susana’s apartment in Mexico City on fire, intending to kill her; however, one of Susana's friends is in the apartment and perishes in the fire, leaving her remains unrecognizable and everyone to assume it was Susana who died. Archaeologist Andrés receives Susana's medical care and as time passes, a romance blossoms between her and the archaeologist, even as betrayals and murders surround them, with a local woman, Mayán, plotting against Susana to win over the archaeologist for herself. Eventually, Susana and the archaeologist return to Mexico City. She reveals herself to some family members, but keeps her survival hidden from lawyer Andrés, so she can initiate a divorce after discovering his affair with Ivonne and his takeover of her assets.