Antwi's senior career began in Ghana with Liberty Professionals. In 2015, Slovácko loaned Antwi.[2] However, he returned to Liberty Professionals months later following zero appearances; though was an unused substitute once, on 2 May for an away fixture to Viktoria Plzeň.[1] After returning to his parent club, he subsequently made three appearances during the 2016 Ghanaian Premier League.[1][3][4]
Slavia Prague
In September 2016, Czech First League side Slavia Prague purchased Antwi.[1] He was soon sent out on loan, joining Sigma Olomouc in the following February.[1] Like with Slovácko, he didn't make a first-team appearance for them.[1]
Příbram
On 27 August 2017, Antwi signed a contract with Příbram of the Czech National Football League.[1] He made his professional debut for the club on 29 October versus Baník Sokolov, which was the first of fifteen appearances throughout the 2017–18 campaign; a season that ended with promotion.[1]
International career
Antwi represented the Ghana U20 team during 2015.[5] He was selected for the 2015 African U-20 Championship in Senegal, subsequently winning one cap against Mali in the third-place play-off.[6][7] He was also chosen in Ghana's preliminary squad for the 2015 FIFA U-20 World Cup in New Zealand, but didn't make the final cut.[8]