Embelin

Embelin
Names
Preferred IUPAC name
2,5-Dihydroxy-3-undecylcyclohexa-2,5-diene-1,4-dione
Other names
Embelic acid, Emberine
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.008.164 Edit this at Wikidata
EC Number
  • 208-979-8
KEGG
UNII
  • InChI=1S/C17H26O4/c1-2-3-4-5-6-7-8-9-10-11-13-16(20)14(18)12-15(19)17(13)21/h12,18,21H,2-11H2,1H3
    Key: IRSFLDGTOHBADP-UHFFFAOYSA-N
  • CCCCCCCCCCCC1=C(C(=O)C=C(C1=O)O)O
Properties
C17H26O4
Molar mass 294.391 g·mol−1
Hazards
GHS labelling:
GHS07: Exclamation mark
Warning
H361
P201, P202, P281, P308+P313, P405, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Embelin (2,5-dihydroxy-3-undecyl-1,4-benzoquinone) is a naturally occurring para-benzoquinone isolated from dried berries of Embelia ribes plants.[1][2] Several studies have reported antidiabetic activity of embelin.[3]

References

  1. ^ Radhakrishnan, N., & Gnanamani, A. (2014). 2, 5-dihydroxy-3-undecyl-1, 4-benzoquinone (Embelin)-A second solid gold of India-A Review. International Journal Pharmacy & Pharmaceutical Sciences, 6(6), 23-30.
  2. ^ Poojari, R. (2014). Embelin–a drug of antiquity: shifting the paradigm towards modern medicine. Expert opinion on investigational drugs, 23(3), 427-444. PMID 24397264 doi:10.1517/13543784.2014.867016
  3. ^ Durg, S., Veerapur, V. P., Neelima, S., & Dhadde, S. B. (2017). Antidiabetic activity of Embelia ribes, embelin and its derivatives: A systematic review and meta-analysis. Biomedicine & Pharmacotherapy, 86, 195-204. PMID 27984799 doi:10.1016/j.biopha.2016.12.001